Pictorial Essay Review of Malignancies with low FDG-avidity in PET/CT

Poster #: 033
Session/Time: B
Author: Frank Arthur Watson, BS, MS
Mentor: Kathy Byun, MD
Research Type: Review Article

Abstract

INTRODUCTION:
18-Fluorodeoxyglucose-Positron Emission Tomography/Computerized Tomography (FDG-PET/CT) is a medical imaging technique which utilizes 18-FDG as a radiotracer to map out differences in cell function and metabolic activity for oncologic detection.

MAIN BODY:
One of the drawbacks of 18-FDG PET/CT is that the 18-FDG radioisotope is does not demonstrate avid uptake among every cancer type, and there are recognized factors deriving from both patients and tumors which elicit this phenomenon. We will discuss the factors that affect 18-FDG avidity, show various malignancies that typically present with low 18-FDG avidity, explain attributable factors causing low avidity and propose alternative imaging modalities.

CONCLUSION:
This pictorial essay aims to provide a reference for different malignancies whose detection may potentially be missed or underdiagnosed with 18-FDG PET/CT.