Inferior Turbinate Reduction in Children Undergoing Adenotonsillectomy for Sleep Disordered Breathing
Poster #: 077
Session/Time: B
Author:
Shreyas Srinath Bhalle, MS
Mentor:
Cristina Baldassari, MD
Research Type: Clinical Research
Abstract
INTRODUCTION:
Pediatric sleep disordered breathing (SDB), which impacts up to 5% of school-aged children, can have profound negative impacts on quality of life. Although the pathophysiology of the disorder is multifactorial, adenotonsillar hypertrophy is common in children presenting with SDB. While adenotonsillectomy provides improvement in symptomology, symptoms of obstruction may continue to persist in children treated for SDB. Nasal obstruction, often due to turbinate hypertrophy is a common contributing factor. There are few prospective studies assessing treatment outcomes in children with SDB treated with inferior turbinate reduction (ITR). The objective of the study is to assess whether the addition of ITR to adenotonsillectomy results in greater improvement in symptoms and quality of life compared to adenotonsillectomy alone in children with SDB.
METHODS:
Children between the ages of 3 and 12 with nasal congestion or mouth breathing and greater than ≥75% turbinate obstruction on anterior rhinoscopy are enrolled in one of two groups of 40 participants. Standardized, validated questionnaires including the PSQ, the OSA-18 survey, as well as the NOSE survey were assessed at the visits. Acoustic rhinometry and rhinomanometry flow are performed pre-operatively, and at 3 and 6 months post-operatively. Measurements are taken before and after administration of oxymetazoline. Results/
DISCUSSION:
Recruitment for the study is ongoing. Preliminary analysis of patients with completed baseline and 3-month visits (and some with 6-month follow-up) shows improvement in OSA-18, PSQ, and NOSE scores in both groups. Objective measures of nasal airflow, including acoustic rhinometry and rhinomanometry, also demonstrate improvement postoperatively.
CONCLUSION:
Although recruitment for the study is still ongoing and few patients have completed the study, preliminary data from patients is promising. Patients report significant symptomatic improvement following adenotonsillectomy as well as those with ITR alongside adenotonsillectomy. While early findings are promising, additional enrollment and data collection are needed to determine whether the addition of ITR confers a statistically and clinically significant benefit over AT alone in improving symptomatology and quality of life.
Pediatric sleep disordered breathing (SDB), which impacts up to 5% of school-aged children, can have profound negative impacts on quality of life. Although the pathophysiology of the disorder is multifactorial, adenotonsillar hypertrophy is common in children presenting with SDB. While adenotonsillectomy provides improvement in symptomology, symptoms of obstruction may continue to persist in children treated for SDB. Nasal obstruction, often due to turbinate hypertrophy is a common contributing factor. There are few prospective studies assessing treatment outcomes in children with SDB treated with inferior turbinate reduction (ITR). The objective of the study is to assess whether the addition of ITR to adenotonsillectomy results in greater improvement in symptoms and quality of life compared to adenotonsillectomy alone in children with SDB.
METHODS:
Children between the ages of 3 and 12 with nasal congestion or mouth breathing and greater than ≥75% turbinate obstruction on anterior rhinoscopy are enrolled in one of two groups of 40 participants. Standardized, validated questionnaires including the PSQ, the OSA-18 survey, as well as the NOSE survey were assessed at the visits. Acoustic rhinometry and rhinomanometry flow are performed pre-operatively, and at 3 and 6 months post-operatively. Measurements are taken before and after administration of oxymetazoline. Results/
DISCUSSION:
Recruitment for the study is ongoing. Preliminary analysis of patients with completed baseline and 3-month visits (and some with 6-month follow-up) shows improvement in OSA-18, PSQ, and NOSE scores in both groups. Objective measures of nasal airflow, including acoustic rhinometry and rhinomanometry, also demonstrate improvement postoperatively.
CONCLUSION:
Although recruitment for the study is still ongoing and few patients have completed the study, preliminary data from patients is promising. Patients report significant symptomatic improvement following adenotonsillectomy as well as those with ITR alongside adenotonsillectomy. While early findings are promising, additional enrollment and data collection are needed to determine whether the addition of ITR confers a statistically and clinically significant benefit over AT alone in improving symptomatology and quality of life.