About
We aim to serve all faculty, fellows, residents, and students with research support needs in order to improve the quality and long-term success of scientific research. This page is meant to provide the epidemiology and biostatistics background to better prepare researchers to plan and conduct their own research studies as well as better prepare them for their collaborative work with our RISE team.
Biostatistics Training & Practice
This GraphPad guide examines general principles of statistical analyses, looks at how to conduct those analyses using the GraphPad statistical program Prism, and how to interpret results. See the Principles of Statistics page to review some important issues in statistics, and Guided Examples of Statistical Analyses page for examples of some common statistical analyses using Prism, including descriptive statistics, comparing two groups, and diagnostic tests.
GraphPad Prism offers GraphPad Quick Calcs which can be used to view and become comfortable with the way in which data needs to be entered depending upon the statistical test. There are many other software options available, some of which are free for use. While using GraphPad Quick Calcs, choose the type of data and analysis you have or would like to run and follow the prompts for entering data and conducting your analysis.
Epidemiology & Study Design Info
If you'd like to review or plan on becoming involved in clinical trials, please see clinicaltrials.gov. This site provides the current status of privately and publicly funded clinical studies. Further, many devices, biologics, etc. are required by law to be registered via clinicaltrials.gov.
The RISE team has collected a list of publicly available datasets and data warehouses that can be used to answer a variety of research questions. The data listed covers a myriad of topics including insurance coverage, drug use, social vulnerability, community surveys, census records, food access and nutrition, geography and rural-urban planning, and more. Data sources come from both survey collection, electronic medical records, and government mandated data collection.
Please see the table below to access the data source list.
This document will continue to be amended with new data sources as we find them. If you know of any you would like to have included on this list, then please contact us at RISE@odu.edu.
For any data used from this spreadsheet please remember to submit an IRB proposal stating your intentions with the dataset you plan to use.
| Dataset/Database collection name | Link | Database or Data Repository | Deidentified | Years | Provider | Cost | Training Required | Dataset type | Population | Geography | Data Modalities | NOTES |
| PhysioNet | PhysioNet | Data Repository | Varies | Varies | MIT Laboratory for Computational Physiology | Free | CITI and Data Use Agreements | Varies | Varies | Varies | Demographics, labs, medications, diagnoses, etc. | |
| eICU Collaborative Research Database | eICU | Database | Yes | 2014-2015 | Philips Healthcare/MIT | Free | Training course | Electronic Health Record | ICU patients from U.S. hospitals | US | Demographics, vital signs, lab results, medications, diagnoses, treatments | |
| Medicare COVID-19 Vaccine PUF | Centers for Medicare and Medicaid Services | Database | Aggregated public-use | 2020-2022 | Centers for Medicare and Medicaid Services | Free | None | Medicare claims/public-health utilization and spending | Medicare Fee-to-Service beneficiaires receiving COVID-19 vaccines | US | Claims-based vaccination utilization and spending | |
| HINTS-SEER | HINTS-SEER | Database | Yes | 2021 | NCI | Free | None | Survey | Cancer survivors in US | US | Information, knowledge, risk behaviors | *** need to submit a request |
| Population Assessment of Tobacco and Health (PATH) | PATH | Database | Yes | 2013-2024 | NIDA | Free | None, but recommended to complete a training on linking files | Survey | US adults | US | Behaviors, attitudes, biomarkers, and health outcomes associated with tobacco use | *** multiple levels of access |
| Medical Expenditure Panel Survey (MEPS) | AHRQ MEPS | Database | Yes | 1996-2024 | AHRQ | Free | None | Survey | US adults, medical providers | US | Cost and use of healthcare and health insurance | |
| National Survey on Drug Use and Health (NSDUH) | NSDUH | Database | Yes | 1979-2024 | SAMHSA | Free | None | Survey | US adolescents and adults (12+) | US | Tobacco, alcohol, drug use, mental health, and health data | |
| National Health Interview Survey (NHIS) | NHIS | Database | Yes | 2019-2025 | CDC | Free | None | Survey | US adults | US | Numerous health topics | *** need to request access |
| General Social Survey (GSS) | GSS | Database | Yes | 1972-2025 | NORC | Free | None | Survey | US adults | US | Behavioral and attitudinal questions about civil liberties, crime, violence, morality, stress | |
| Behavioral Risk Factor Surveillance System (BRFSS) | BRFSS | Database | Yes | 1991-present | CDC | Free | None | Survey | US adults | US | Prevalence data among adult U.S. residents regarding their risk behaviors and preventive health practices | |
| Neighborhood Atlas Area Deprivation Index | Neighborhood Atlas Area Deprivation Index | Database | Yes | 2010-2020 | Center for Health Disparities Research, University of Wisconsin | Free | Varies, possible DUAs | Survey | US adults | US | Composite neighborhood deprivation score (income, education, housing, etc.) | |
| CDC Social Vulnerability Index (SVI) | SVI | Database | Yes | 2010-2020 | CDC | Free | None | Geographic split | US population | US | Socioeconomic status, household composition, minority status, housing type, etc. | *** Only done every other year (2010, 2012, 2014, and so on) |
| USDA Food Access Research Atlas | USDA Food Atlas | Database | Yes | 2010, 2015, 2019 | USDA | Free | None | Census Tract from ZIP | US population | US | Food desert flags, low access population, SNAP participation | |
| HRSA Health Professional Shortage areas | HRSA Shortage Area | Database | Yes | Updated daily | Health Resources and Services Administration | Free | None | Varies | US population | US | Primary care shortage designation, HPSA score, provider to population ratio | *** HPSA is one of many files available from HRSA |
| County Health Rankings | County Health Rankings | Database | Yes | 2010-2020 | Virginia Department of Health | Free | None | County based split | US population | US | Health outcomes rank, health factors rank, preventable hospital stays rate, etc. | |
| American Community Survey | ACS | Database | Yes | 2010-2020 | Census | Free | None | Zip code based split | US population | US | Median household income, % below poverty, % with severe housing cost burden, etc. | *** Updates every 5 years (2010, 2015, 2020, etc.) |
| ACS SNAP/Food Stamps Receipt | ACS SNAP | Database | Yes | 2016-Present | Census | Free | None | 5 year estimates | US population | US | Primary exposure, percent of households receiving SNAP, ZCTA level | |
| ACS Demographic and Housing Estimates | ACS Housing | Database | Yes | 2010-2024 | Census | Free | None | Yearly estimates | US population | US | ZCTA adult population (18+) as the denominator/offset | |
| USDA ERS Rural-Urban Commuting Area (RUCA) codes | USDA Commuting Codes | Database | Yes | 1990-2020 | USDA | Free | None | Zip code based split | US population | US | Rurality, ZIP-level RUCA categories | |
| HUD USPS ZIP crosswalk files | USPS Crosswalk | Database | Yes | 2010-2026 | Office of Policy Development and Research | Free | None | Zip code based split | US population | US | Quarterly Residential Crosswlak for ZIP level linkage | ***Will need to register with the website |
| Health Data.gov | Health.gov | Database repository | Yes | Varies | US HHS | Free | None | Varies | US population | US | Demographics, socioeconomic factors, geospatial | |
| Truveta Data | Truveta | Database | Yes | Varies | Truveta | Unknown | Unknown | Electronic Health Record | Patients from 30 US health systems | US | Demographics, labs, imaging, claims, mortality, pediatric/mother data, admission-discharge-transfer data, insurance payer data, genomics | ***Sentara Health is cofounder of this HER, however, I did not get a response when I inquire about data access process. |
| National Center for Health Statistics | CDC Health Stats | Database repository | Yes | Varies | CDC | Free | None | Varies | US population | US | Demographics, health behaviors, comorbidities, health outcomes, cancer mental health, vaccination | |
| National Health and Nutrition Examination Survey (NHANES) | NHANES | Database | Yes | 1999-present | CDC | Free | None | Survey, health exams, and lab testing | US adults & children | US | Interviews about health, diet, and personal, social, and economic characteristics; dental exams and health and body measurements; tests on blood, urine, DNA, oral swabs & rinses. | *** restricted data of geographic variables and DNA can be requested. Can be linked with Medicare and Medicaid data. |
| CDC Wonder (Wide-ranging ONline Data for Epidemiologic Research) | CDC Wonder | Database | Aggregated public-use | Varies | CDC | Free | None | Aggregate-level (year, geolocation, demographics) | Varies | US | Ad-hoc queries for mortality, natality, population, environmental and other public health datasets; outputs are counts and rates. | *** query results can be exported. |
| Healthcare Cost and Utilization Project (HCUP) | HCUP | Database | Yes | Varies | AHRQ | with fee | None | Hospital encounters | Varies | US | Various databases cover inpatient, emergency department, pediatric inpatient, and ambulatory surgery settings. | ***need to submit a request; 80% off for students |
| National Health and Aging Trends Study (NHATS) | NHATS | Database | Yes | 2011-present | Johns Hopkins & U Mich | Free | None | Survey | 65 and older Medicare beneficiaries | US | In-person interviews collect detailed information on the disablement process and its consequences. | *** need to register to access data |
| National Longitudinal Study of Adolescent to Adult Health (Add Health) | Add Health | Database | Yes | 1994-present | UNC Chapel Hill | Free | None | Survey + biomarkers + physical measures for later waves | Adolescents in grades 7-12 in the 1994-95 school year | US | Longitudinal study of adolescents. Demographic, social, familial, behavioral, psychosocial, cognitive, and health survey data from participants and their parents; contextual data from participants’ schools, neighborhoods, and geographies of residence; and in-home physical and biological data from participants, including genetic markers, blood-based assays, anthropometric measures, and medications. | *** The public-use data sets contain all the survey data but only for a subset of the full Add Health sample. |
Questions?
Please contact the RISE helpdesk if you have any questions.