Assistant Professor
Medical Diagnostic & Translational Sciences

Peter Mollica

Suite 365 4211 Monarch Way
Norfolk, 23529

High-complexity Clinical Laboratory Director (HCLD)
Sponsoring Organization: American Board of Bioanalysis
Date Obtained: 2022-12-01
MB(ASCP)CM
Sponsoring Organization: American Society of Clinical Pathology
Date Obtained: 2015-11-15

Contracts, Grants and Sponsored Research

Mollica, P. and Xiao, S. "Investigation of psPEF on pathological protein aggregates in HD and AD neural stem cells" $24,000. Old Dominion University. May 10, 2020 - May 9, 2021
Mollica, P. Anthony., Riethman, H. C., Sachs, P. C., Bruno, R. D. and Kraj, B. J. "COVID-19 Testing Facility Development" $118,270. Old Dominion University. May 1, 2020 - August 31, 2020
Mollica, P., Bruno, R., Sachs, P. and Xiao, S. "Investigating the effects of sub-nanosecond pulsed electric fields as a potential protein disaggregation agent in Huntington’s disease and Alzheimer’s disease neurons" $45,000. State. July 1, 2018 - September 30, 2019

Expertise

Clinical Supervision
Development of CLIA-Certified Molecular Diagnostics Laboratory (Monarch Molecular). As technical supervisor, general supervisor, and on-site director designee, I oversee all aspects of testing clinical patient specimens to ensure CMS/CLIA compliance.
Biotechnology
Induced pluripotent stem cells; Piosecond pulse electric fields; Tissue engineering;
Biomaterials
Human neural engineering; Human neuronal electrophysiology
Cancer
Breast cancer modeling; Three-dimension tumor creation
3D Printing
Bioprinting

Articles

Rossi, A., Pakhomova, O., Mollica, P., Casciola, M., Mangalanathan, U., Pakhomov, A. and Muratori, C. (2019). Nanosecond Pulsed Electric Fields Induce Endoplasmic Reticulum Stress Accompanied by Immunogenic Cell Death in Murine Models of Lymphoma and Colorectal Cancer.. Cancers 11 (12).
Mollica, P., Booth-Creech, E. N., Reid, J. A., Zamponi, M., Sullivan, S. M., Palmer, X. L., Sachs, P. and Bruno, R. (2019). 3D bioprinted mammary organoids and tumoroids in human mammary derived ECM hydrogels.. Acta biomaterialia 95 , pp. 201-213.
Reid, J. A., Palmer, X. L., Mollica, P., Northam, N., Sachs, P. and Bruno, R. (2019). A 3D bioprinter platform for mechanistic analysis of tumoroids and chimeric mammary organoids.. Scientific reports 9 (1) , pp. 7466.
Rossi, A., Pakhomova, O., Pakhomov, A., Weygandt, S., Bulysheva, A., Murray, L. E., Mollica, P. and Muratori, C. (2019). Mechanisms and immunogenicity of nsPEF-induced cell death in B16F10 melanoma tumors.. Scientific reports 9 (1) , pp. 431.
Reid, J. A., Mollica, P., Bruno, R. and Sachs, P. (2018). Correction to: Consistent and reproducible cultures of large-scale 3D mammary epithelial structures using an accessible bioprinting platform.. Breast cancer research : BCR 20 (1) , pp. 136.
Reid, J. A., Mollica, P., Bruno, R. and Sachs, P. (2018). Consistent and reproducible cultures of large-scale 3D mammary epithelial structures using an accessible bioprinting platform.. Breast cancer research : BCR 20 (1) , pp. 122.
Petrella, R. A., Mollica, P., Zamponi, M., Reid, J. A., Xiao, S., Bruno, R. and Sachs, P. (2018). 3D bioprinter applied picosecond pulsed electric fields for targeted manipulation of proliferation and lineage specific gene expression in neural stem cells.. Journal of neural engineering 15 (5) , pp. 056021.
Wu, V., Auchman, M., Mollica, P., Sachs, P. and Bruno, R. (2018). ALDH1A1 positive cells are a unique component of the tonsillar crypt niche and are lost along with NGFR positive stem cells during tumourigenesis.. Pathology 50 (5) , pp. 524-529.
Mollica, P., Zamponi, M., Reid, J. A., Sharma, D. K., White, A. E., Ogle, R., Bruno, R. and Sachs, P. (2018). Epigenetic alterations mediate iPSC-induced normalization of DNA repair gene expression and TNR stability in Huntington's disease cells.. Journal of cell science 131 (13).
Muratori, C., Pakhomov, A., Gianulis, E., Meads, J., Casciola, M., Mollica, P. and Pakhomova, O. (2017). Activation of the phospholipid scramblase TMEM16F by nanosecond pulsed electric fields (nsPEF) facilitates its diverse cytophysiological effects.. The Journal of biological chemistry 292 (47) , pp. 19381-19391.
Sachs, P., Mollica, P. and Bruno, R. (2017). Tissue specific microenvironments: a key tool for tissue engineering and regenerative medicine.. Journal of biological engineering 11 , pp. 34.
Mollica, P., Reid, J. A., Ogle, R., Sachs, P. and Bruno, R. (2016). DNA Methylation Leads to DNA Repair Gene Down-Regulation and Trinucleotide Repeat Expansion in Patient-Derived Huntington Disease Cells.. The American journal of pathology 186 (7) , pp. 1967-1976.
Reid, J. A., Mollica, P., Johnson, G. D., Ogle, R., Bruno, R. and Sachs, P. (2016). Accessible bioprinting: adaptation of a low-cost 3D-printer for precise cell placement and stem cell differentiation.. Biofabrication 8 (2) , pp. 025017.