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- Holly Gaff
- Assistant Professor
- 302a Mills Godwin Bldg
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Norfolk,
VA
23529
- 757-683-6903
- hgaff@odu.edu
- Web Page
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Education
- University Of Tennessee - Knoxville,
1999
- Major: Mathematics
- Degree: Ph. D.
- Taylor University,
1993
- Major: Mathematics and Environmental Science
- Degree: B.S.
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Research Interests
- mathematical modeling and computer simulation of infectious diseases with specific interest in tick-borne diseases
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Book Chapters
- Gaff, H., and Schaefer, E. (2008). Modeling parasitic Disease Transmission: Biology to Control.. Austin, TX: Biosceince / Eureukah.
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Articles
- Fedrow, A., Wright, C., Gaff, H., Sonenshine, D., Hynes, W. L., and Richards, A. (2012). In vitro propagation of Candidatus Rickettsia andeanae isolated from Amblyomma maculatum. FEMS Immunology and Medical Microbiology, 64 (74-81),
- Gaff, H., Lyons, M. M., and Watson, G. S. Classroom Manipulative to Engage Students in Mathematical Modeling of Disease Spread: 1+1 = Achoo!. Mathematical Modeling of Natural Phenomena
- Tracy, L., Gaff, H., Burgess, C., Sow, S., Gravitt, P. E., and Tracy, J. K. (2011). Estimating the impact of a single vaccination campaign versus screening strategy on cervical cancer incidence in Mali. Clinical Infectious Diseases, 52 (5), (pp. 641-645).
- Mukandavire, Z., Liao, S., Wang, J., Gaff, H., Smith, D., and Morris, J. G. (2011). Estimating the reproductive numbers for the 2008-2009 cholera outbreaks in Zimbabwe. Proceedings of the National Academies, 108 (21), (pp. 8767-8772).
- Nadolny, R. M., Wright, C. L., Hynes, W. L., Sonenshine, D., and Gaff, H. (2011). Ixodes affinis (Acari: Ixodidae) in southeastern Virginia and implications for the spread of Borrelia burgdorferi, the agent
of Lyme disease. Journal of Vector Ecology, 36 (2), (pp. 464 - 467).
- Gaff, H., Burgess, C., Jackson, J., Niu, T., Papelis, Y., and Hartley, D. (2011). Mathematical model to assess the relative effectiveness of Rift Valley fever countermeasures. International Journal of Artificial Life Research, 2 (2), (pp. 1-18).
- Gaff, H., and Schaefer, E. Modeling control of a tick-borne disease. Journal of Biological Dynamics
- Agheksanterian, A., Gobbert, M. K., Fister, K. R., Gaff, H., Lenhart, S., and Schaefer, E. Modeling the spread of epidemic cholera: an age-structured model. Nonlinear Analysis: Real World Applications
- Hartley, D. M., Rinderknecht, J. L., Nipp, T. L., Clarke, N. P., Snowder, G. D., and Advisory Group, F. R. (2011). Potential Effects of Rift Valley Fever in the United States. Emerging Infectious Diseases, 17 (8),
- Gaff, H. (2011). Preliminary analysis of an agent-based model for a tick-borne disease. Mathematical Biosciences and Engineering, 8 (2), (pp. 465–475).
- Wright, C., Nadolny, R., Jiang, J., Richards, A., Sonenshine, D., Gaff, H., and Hynes, W. L. (2011). Tidewater Spotted Fever: Detection of Rickettsia parkeri in Gulf Coast ticks, southeastern Virginia. Emerging Infectious Diseases, 17 (5), (pp. 896-898).
- Niu, T., Gaff, H., Papelis, Y. E., and Hartley, D. M. An Epidemiological Model of Rift Valley Fever with Spatial Dynamics.
- Jungck, J. R., Gaff, H., Fagen, A., and Lobov, J. B. (2010). From the National Academies "Beyond BIO2010: Celebration and Opportunities" at the Intersection of Biology. CBE--Life Sciences Education, 9 (3), (pp. 143-147).
- Jungck, J. R., Gaff, H., and Weisstein, A. (2010). Mathematical Manipulative Models: "In Defense of Beanbag". CBE--Life Sciences Education, 9 (3), (pp. 201-211).
- Neilan, R. M., Schaefer, E., Gaff, H., Fister, K. R., and Lenhart, S. (2010). Modeling Optimal Intervention Strategies for Cholera. Bulletin of Mathematical Biology, 72 (8), (pp. 2004-2018).
- Lyons, M. M., Ward, J. E., Gaff, H., Hicks, R., Drake, J., and Dobbs, F. (2010). Theory of island biogeography on a microscopic scale: organic aggregates as islands for aquatic pathogens. Aquatic Microbial Ecology, 60 (1),
- Gaff, H., and Schaefer, E. (2009). Optimal control applied to vaccination and treatment strategies for various epidemiological models. Mathematical Biosciences and Engineering, 6, (pp. 469-492).
- Watson, G. S., Marken, J. A., Wiles, L., Curry-Lourenco, K. A., Perencevich, E. N., Sechrist, S. R., and Gaff, H. Use of a Simulated Substance to Imitate Infection in a Nurse Training Program. Quality and Safety in Health Care
- Duke-Sylvester, S. M., Perencevich, E. N., Furuno, J. P., Real, L. A., and Gaff, H. (2008). Advancing epidemiological science through computational modeling: a review with novel examples. Annales Zoologici Fennici, 45, (pp. 385-401).
- Gaff, H., Gross, L., and Schaefer, E. (2008). Results from a mathematical model for human monocytic ehrlichiosis. Clinical Microbiology and Infection, 15 (s2), (pp. 15-16).
- Gaff, H., Gross, L., and Schaefer, E. (2008). Results from a metapopulation model for Human Monocytic Ehrlichiosis (HME). Fifth International Conference on Rickettsiae and Rickettsial Diseases
- Gaff, H., Hartley, D., and Leahy, N. (2007). An epidemiological modelfor Rift Valley fever virus. Electronic Journal of Differential Equations, 2007 115, (pp. 1-12).
- Gaff, H., and Gross, L. J. (2007). Analysis of a tick-borne disease model with varying populaton sizes in various habitats. Bulletin of Mathematical Biology, 69, (pp. 265-288).
- Joshi, H. R., Lenhart, S., Lou, H., and Gaff, H. (2007). Harvesting Control in an integrodifference population model with concave growth term. Nonlinear Analysis: Hybrid Systems, 1, (pp. 417-429).
- Gaff, H., Joshi, H. R., and Lenhart, S. (2007). Optimal harvesting during an invasion of a sublethal plan pathogen. Environmental and Development Economics, 12, (pp. 673-686).
- Furuno, J. P., Harris, A. D., Wright, M. O., Hartley, D. M., McGregor, J. C., Gaff, H., Hebden, J. N., Standiford, H. C., and Perencevich, E. N. (2007). Utility of active surveillance culturing for methicillin-resistant Staphylococcus aureus upon intensive care unit discharge.. Infection Control and Hospital Epidemiology, 28, (pp. 666-670).
- Joshi, H. R., Lenhardt, S., and Gaff, H. (2006). Optimal harvesting in an integro-difference population model. Optimal Control Applications and Methods, 26, (pp. 61-75).
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Presentations
- In vitro propagation of Candidatus Rickettsia andeanae isolated from Amblyomma maculatum
- Conference Name:
- Location: Herklion, Crete, Greece
- Authors/Presenters:
, F. A.
, W. C.
Gaff, H.
Sonenshine, D.
Hynes, W. L.
, R. A.
- Tidewater spotted fever: detection of Rickettsia parkeri in Gulf Coast ticks, Southeastern Virginia
- Conference Name:
- Location: Herklion, Crete, Greece
- Authors/Presenters:
Gaff, H.
Hynes, W. L.
, J. J.
, N. R.
, R. A.
Sonenshine, D.
, W. C.
- Agent-based models of interacting populations
- Conference Name: SMB
- Sponsoring Organization: SMB
- Location: Krakow, Poland
- Date: July, 2011
- Authors/Presenters:
Gaff, H.
- Overview: Reports from US - African BioMathematics Initiative: Conservation Biology
- Conference Name: SMB
- Sponsoring Organization: SMB
- Location: Krakow, Poland
- Date: July, 2011
- Authors/Presenters:
Gaff, H.
- Results from tick survey in Southeastern Virginia, USA , and application to mathematical modeling
- Conference Name: ASR
- Sponsoring Organization: ASR
- Location: Heraklion, Greece
- Date: May, 2011
- Authors/Presenters:
Gaff, H.
- Survey of Ticks in the Hampton Roads area: Mathematical Modeling
- Conference Name: VMCA
- Sponsoring Organization: VMCA
- Location: Virginia Beach, VA
- Date: February, 2011
- Authors/Presenters:
Gaff, H. Presenter & Author
Nadolny, R. Author Only
Wright, C. Author Only
Hynes, W. L. Author Only
Sonenshine, D. Author Only
- Survey of Ticks in the Hampton Roads area: Rickettsia parkeri
- Conference Name: VMCA
- Sponsoring Organization: VMCA
- Location: Virginia Beach, VA
- Date: February, 2011
- Authors/Presenters:
Wright, C. Presenter & Author
Gaff, H. Author Only
Nadolny, R. Author Only
Sonenshine, D. Author Only
Hynes, W. L. Author Only
- Survey of Ticks in the Hampton Roads area: Tick populations
- Conference Name: VMCA
- Sponsoring Organization: VMCA
- Location: Virginia Beach, VA
- Date: February, 2011
- Authors/Presenters:
Nadolny, R. Presenter & Author
Gaff, H. Author Only
Wright, C. Author Only
Hynes, W. L. Author Only
Sonenshine, D. Author Only
- Estimating tick-borne disease risk with an agent-based model
- Conference Name: AMS
- Sponsoring Organization: AMS
- Location: Richmond, VA
- Date: November, 2010
- Authors/Presenters:
Gaff, H.
- Tidewater spotted fever: detection of R. parkeri in gulf coast ticks in southeastern Virginia
- Conference Name: VA Branch of the American Society for Microbiology
- Sponsoring Organization: VA Branch of the American Society for Microbiology
- Location: Lynchburg, VA
- Date: November 5, 2010
- Authors/Presenters:
Wright, C. Presenter Only
Nadolny, R. Author Only
Sonenshine, D. Author Only
Gaff, H. Author Only
Hynes, W. L. Author Only
- Mathematical modeling of the control of a tick-borne disease
- Conference Name:
- Location: Pittsburgh, Pennsylvania
- Date: July, 2010
- Authors/Presenters:
Gaff, H. Presenter & Author
- An initial mathematical model of the eco-epidemiology of mycobacteriosis in striped bass
- Conference Name: USGS
- Sponsoring Organization: USGS
- Location: Leetown, West Virginia
- Date: May, 2010
- Authors/Presenters:
Gaff, H.
- Modeling spread of tick-borne disease
- Conference Name: Tel Aviv University
- Sponsoring Organization: Tel Aviv University
- Location: Israel
- Date: January 5, 2010
- Authors/Presenters:
Gaff, H.
- Graduate School Opportunities
- Conference Name: University of Tennessee
- Sponsoring Organization: University of Tennessee
- Location: Knoxville, TN
- Date: October 24, 2009
- Authors/Presenters:
Gaff, H.
- Optimal control of a tick-borne disease model
- Conference Name: University of Alabama
- Sponsoring Organization: University of Alabama
- Location: Huntsville, AL
- Date: October 9, 2009
- Authors/Presenters:
Gaff, H.
- Preliminary report: An individual-based model of tick-borne disease
- Conference Name:
- Location: Hilton Head, South Carolina
- Date: August, 2009
- Authors/Presenters:
Gaff, H.
- Effects of migration on tick-borne disease risk
- Conference Name: Society of Mathematical Biology
- Sponsoring Organization: Society of Mathematical Biology
- Location: Vancouver, BR
- Date: July, 2009
- Authors/Presenters:
Gaff, H.
- Teaching the biology and ecology of infectious disease through mathematics
- Conference Name: BIOED 2009
- Sponsoring Organization: BIOED 2009
- Location: Christchurch, New Zealand
- Date: February, 2009
- Authors/Presenters:
Gaff, H.
- Metapopulation models in tick-borne disease transmission modeling
- Conference Name: Joint Mathematics Meeting
- Sponsoring Organization: Joint Mathematics Meeting
- Location: Washington, DC
- Date: January, 2009
- Authors/Presenters:
Gaff, H.
Schaefer, E.
- Ticks, Mosquitoes, Diseases, and Mathematics
- Conference Name: Mathematics Association of America
- Sponsoring Organization: Mathematics Association of America
- Location: St. Michael's College, Vermont
- Date: 2008
- Authors/Presenters:
Gaff, H.
- Optimal control of metapopulation tick model
- Conference Name: Society of Mathematical Biology
- Sponsoring Organization: Society of Mathematical Biology
- Location: Toronto
- Date: 2008
- Authors/Presenters:
Gaff, H.
- A Pilot Study to Assess the Impact of Various Infection Control Educational Tecniques and Practies on the Spread of Methicillin-Resistant
Staphylococcus aureus in a Virtual Intensive Care Unit
- Conference Name: Old Dominion University, Office of Research
- Sponsoring Organization: Old Dominion University, Office of Research
- Location: Norfolk, VA
- Date: October 31, 2008
- Authors/Presenters:
Curry-Lourenco, K. A.
Gaff, H. Presenter & Author
Marken, J. A.
Pevencevich, E. N.
Sechrist, S. R.
Watson, G. S. Presenter & Author
Wiles, L.
- Modeling the emergence and transmission of Rift Valley fever
- Conference Name:
- Location: Nagasaki, Japan
- Date: May, 2008
- Authors/Presenters:
Gaff, H.
- Results from a metapopulation model for Human Monocytic Ehrlichiosis (HME)
- Conference Name:
- Location: Marseille, France
- Date: May, 2008
- Authors/Presenters:
Gaff, H.
- Conference Name: MathFest
- Sponsoring Organization: MathFest
- Location: San Jose, CA
- Date: 2007
- Authors/Presenters:
Gaff, H.
- Conference Name: The Institute for Mathematical Biology Education and Resources
- Sponsoring Organization: The Institute for Mathematical Biology Education and Resources
- Location: Appalachian State University
- Date: November, 2007
- Authors/Presenters:
Gaff, H.
- Modeling tick-borne diseases: a metapopulation model
- Conference Name: Society of for Mathematical Biology and the Japanese Society for Mathematical Biology
- Sponsoring Organization: Society of for Mathematical Biology and the Japanese Society for Mathematical Biology
- Location: San Jose, CA
- Date: August, 2007
- Authors/Presenters:
Gaff, H.
- Making Models Useful to Decision-Makers
- Sponsoring Organization: Joint Mathematics Meeting
- Location: New Orleans
- Date: January, 2007
- Authors/Presenters:
Gaff, H.
- Optimal harvesting during an invasion of a sublethal plant pathogen
- Conference Name:
- Location: San Antonio, Texas
- Date: January, 2006
- Authors/Presenters:
Gaff, H.
- From Graduate School to a Tenure-Track Faculty Position Via the Scenic Route
- Conference Name: SIAM
- Sponsoring Organization: SIAM
- Date: July, 2005
- Authors/Presenters:
Gaff, H.
- Optimal control of a simplified tick-borne disease model
- Conference Name:
- Date: July, 2005
- Authors/Presenters:
Gaff, H.
- A Tick-Borne Disease Model - Spread adn Control of Ehrlichiosis
- Conference Name: Murray State University
- Sponsoring Organization: Murray State University
- Location: Murray, Kentucky
- Date: June, 2005
- Authors/Presenters:
Gaff, H.
- A tick-borne disease model
- Conference Name:
- Location: Trieste, Italy
- Date: April, 2005
- Authors/Presenters:
Gaff, H.
- 2010: Shining Star Award for Helping students succeed academically, professionally, or personally inside and outside of the classroom
setting, Old Dominion University Division of Student Affairs
- 2010: Shining Star Award for Helping students succeed academically, professionally, or personally inside and outside of the classroom
setting, Old Dominion University Division of Student Affairs
- 2011: Shining Star Award for Helping students succeed academically, professionally, or personally inside and outside of the classroom
setting, Old Dominion University Division of Student Affairs
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Contracts, Grants and Sponsored Research