Updated CV (click)

  Selected Recent Publications

Research Papers Published since Fall 2000

40. Y. Song, P. D. Nallathamby, T. Huang, H. Elsayled-Ali, X. Xu*, “Correlation and Characterization of 3D Morphological Dependent Localized Surface Plasmon Resonance Spectra of Single Silver Nanoparticles Using Dark-field Optical Microscopy and Spectroscopy and AFM”, J. Phys. Chem. C. (2009)  (ASAP article: Nov. 4, 2009; DOI: 10.1021/jp9083019)   

39. H. Xu, P. D. Nallathamby, X. Xu*, “Real-time Imaging and Tuning Subcellular Structures and Membrane Transport Kinetics of Single Live Cells at Nanosecond Regime”, J. Phys. Chem. B. 113, 14393-14404 (2009)

38. L. Browning, K. J. Lee, T. Huang, P. D. Nallathamby, J. Lowman, X. Xu*, “Random Walk of Single Gold Nanoparticles in Zebrafish Embryos Leading to Stochastic Toxic Effects on Embryonic Developments”, Nanoscale 1, 138-152 (2009)

37. T. Huang, P. D. Nallathamby, X. Xu*, “Photostable Single-Molecule Nanoparticle Optical Biosensors for Real-time Sensing of Single Cytokine Molecules and Their Binding Reasctions”, J. Am. Chem. Soc. 130, 17095-17105 (2008)

36. P. D. Nallathamby, K. J. Lee, X. Xu*, “Design of Stable and Uniform Single Nanoparticle Photonics for In Vivo Dynamics Imaging of Nanoenvironments of Zebrafish Embryonic Fluids”, ACS Nano, 2, 1371-1380 (2008)

35. T. Huang, P. D. Nallathamby, D. Gillet, X. Xu*, “Design and Synthesis of Single Nanoparticle Optical Biosensors for Imaging and Characterization of Single Receptor Molecules on Single Living Cells”, Anal. Chem. 79, 7708-7718 (2007). 

 

34. K. J. Lee, P. D. Nallathamby, L. Browning, C. J. Osgood, X. Xu*, “In Vivo Imaging of Transport and Biocompatibility of Single Nanoparticles in Early Development of Zebrafish Embryos”, ACS Nano 1, 133-143 (2007). (ACS Nano Movie, lab tour with Kerry and Prakash; the most-accessed article published in ACS Nano in 2007)

 

33. X. Xu*, "New Frontiers in Ultrasensitive Bioanalysis: Advanced Analytical Chemistry Applications in Nanobiotechnology, Single Molecule Detection, and Single Cell Analysis", a Wiley Chemical Analysis Series, 2007 (invited). 

 

32. X. Xu*, “Outlooks of ultrasensitive detection in bioanalysis” in New Frontiers in Ultrasensitive Bioanalysis: Advanced Analytical Chemistry Applications in Nanobiotechnology, Single Molecule Detection, and Single Cell Analysis, X. Xu, Ed., Wiley, 2007 (invited).

 

31. X. Xu*, Y. Zu, “New bioanalytical applications of electrochemiluminescence” in New Frontiers in Ultrasensitive Bioanalysis: Advanced Analytical Chemistry Applications in Nanobiotechnology, Single Molecule Detection, and Single Cell Analysis, X. Xu, Ed., Wiley, 2007 (invited).

 

30. X Xu*, Y. Song, P. D. Nallathamby, “Probing membrane transport of single live cells using single molecule detection and single nanoparticle assay” in New Frontiers in Ultrasensitive Bioanalysis: Advanced Analytical Chemistry Applications in Nanobiotechnology, Single Molecule Detection, and Single Cell Analysis, X. Xu, Ed., Wiley, 2007 (invited).

 

29. X. Xu*, R. Patel, “Imaging and assembly of nanoparticles in biological systems” in Handbook of Nanostructured Biomaterials and Their Applications in Nanobiotechnology, H. S. Nalwa, Ed., American Scientific Publishers, Vol. 1, Chapter 13, 435-456, 2005 (invited).

 

28. X. Xu*, S. Huang, W. Brownlow, K. Salatia, R. Jeffers, “Size and Temperature Dependence of Surface Plasmon Absorption of Gold Nanoparticles Induced by Tris(2,2'-bipyridine)ruthenium(II)” J. Phys. Chem. B. 108, 15543-15551 (2004).   

27. X. Xu*, W. Brownlow, S. Kyriacou, Q. Wan, and J. Viola, “Real-time Probing of Membrane Transport in Living Microbial Cells Using Single Nanoparticle Optics and Living Cell Imaging" Biochemistry 43 (32), 10400-10413 (2004).    

26. X. Xu*, R. Patel, “Imaging and Assembly of Nanoparticles in Biological Systems”, in Handbook of Nanostructured Biomaterials and Their Applications in Nanobiotechnology, H. S. Nalwa, Ed., American Scientific Publishers, Vol. 1, Chapter 13, 435-456, 2005 (invited).

25. S. Kyriacou, W. Brownlow, X. Xu*, “Using Nanoparticle Optics Assay for Direct Observation of Functions of Antimicrobial Agents in Single Live Bacterial Cells” Biochemistry 43, 140-147 (2004).   

24. X. Xu*, R. Patel, “Nanoparticles for live cell dynamics”, in Encyclopedia of Nanoscience and Nanotechnology, American Scientific Publishers, Vol. 7, 181-192, 2004 (invited).

23. C. Steel, Q. Wan, X. Xu*, “Single live cell imaging of chromosomes in chloramphenicol-induced filamentous Pseudomonas aeruginosa” Biochemistry 43, 175-182, 2004.  

22. X. Xu* , Q. Wan, W. Brownlow, S. Kyriacou, M. Nowak, “Direct Observation of Substrate Induction of Resistance Mechanism in Pseudomonas aeruginosa Using Single Live Cell Imaging " Biochem. Biophys. Res. Commun., 305, 941-949 (2003).

21. X. Xu*, W. Brownlow, S. Huang, J. Chen, "Single Molecule Detection of Efflux Pump Machinery in Pseudomonas aeruginosa " Biochem.

 Biophys. Res. Commun., 305 (1), 79-86 (2003).

20. S. Kyriacou, M. E. Nowak, W. Brownlow, X. Xu*, “Single Live Cell Imaging for Real-time Monitoring of Resistance Mechanism in Pseudomonas aeruginosa " J. Biomedical Optics, 7(4), 576-586 (2002).

19. X. Xu*, J. Chen, R. Jeffers, S. Kyriacou, "Direct Measurement of Sizes and Dynamics of Single Living Membrane Transporters Using Nano-optics ", Nano Letters, 2, 175-182 (2002) (MUST-see real-time videos).

18. X. Xu*, R. Jeffers, S. Kyriacou, "Unconventional Drugs for Inhibition of Bacterium Growth”, US Patent, (pending).

17. X Xu*, R. Jeffers, J. Gao, B. Logan, "Novel Solution-phase Immunoassays for Molecular Analysis of Tumor Markers", Analyst, 126, 1285-1292 (2001) (invited).

16. X. Xu*, J. Gao, R. Jeffers, B. Logan and Z. Wen, "Molecular Analysis of Biomarkers for the Earlier Cancer Detection", Proceedings of SPIE, 3922, 15 (2000).

15. X. Xu, E. S. Yeung, "Long-Range Electrostatic Trapping of Single Protein Molecules at A Liquid/Solid Interface", Science, 281, 1650 (1998).

14. X. Xu, E. S. Yeung, "Direct Measurement of Single-Molecule Diffusion and Photodecomposition in Free Solution", Science, 275, 1106 (1997).

  Representative Publications before 1999

Student Thesis & dissertation

1. S. V. Kyriacou (mentor: X. Xu), “Real-time study of multidrug resistance mechanism in Pseudomonas aeruginosa using nanoparticle optics and single live cell imaging”. Thesis. Old Dominion University, Norfolk, VA (2003).

Book Reviewer

1. X. Xu, J. Am. Chem. Soc., 122, 2144 (2000). "Modern Electrochemistry 1. Volume 1. Ionics", 2 Edition By J. O'M. Bockris.

 Updated Presentations (click)

 Selected Presentations since 1999