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Dr. X. Nancy Xu
Professor in Chemistry and Biochemistry
Track Director of
Biological Chemistry; PhD Program in Biomedical
Sciences (2001-present)
Postdoctoral Fellow Ames Lab-USDOE/Dept. of
Chemistry, Iowa State University (1996-98)
Postdoctoral Fellow The University of Texas at Austin (1993-95)
Ph.D. The
University of Mississippi (12/1992)
BS Xiamen
University (1989/85)
Chemistry and
Biochemistry Department Old Dominion University, Norfolk, VA 23529
Ph.D. Program in Biomedical Sciences: Biological
Chemistry
Application
materials for graduate schools
Dr. X. Nancy Xu Research Group
News:
2012 PHOTON for super-resolution imaging of single live cells (cover of May Issue of Nanoscale)
High-throughput imaging of single NP arrays (cover of Nanoscale)
2011 Elected AAAS Fellow 
Fellows in 2011
PHOTON
for imaging of single protein-ligand binding
complexes (cover of Nanoscale)
Photostable Optical Nanoscopy (PHOTON) (C&EN,
P. 32, June 20, 2011)
New Approaches for Probing of Embryonic Stem Cells
Nano Assays of Multidrug ABC Transporters
2010 Rainbow
Colors of Nanoparticles
New
Uses of Nanoparticles Against
Cancer
Faculty Research Achievement Award
2009 Nanowerk Spotlight
2008 Nanotech
Briefs Nano 50™ Innovator Award; NanoTech Briefs
2007 C&EN Highlight: In Vivo Imaging of Single Ag Nanoparticles
ACS Nano 1,
133 (2007) (Nano Movie,
lab tour)
Nanotech Briefs Nano 50™ Awards in
the Technology,
ODU News; NanoTech Briefs
2006
Single Nanoparticle Optics Featured in NCI Alliance for Nanotechnology in Cancer
Our Research Program in Bionanotechnology Featured in 2006 University Video
NIH and NSF Support of Nano
Research Front Page of Virginian Pilot (Front
Page)
NIH Support of Novel Nanoparticle Assay Featured in ODU News
Welcome to Dr. Xu group: Pursuing of Interface Research at Chemistry,
Biology and Engineering
Laboratory
of Bioanalytical/Biochemistry/Biophysics/Bionanotechnology/Bionanomaterial.
The central theme of our research program is the
development and application of cutting-edge bio- and nano- technologies and
ultrasensitive analytical methodologies to address fundamental and practical
questions in chemical, biochemical and biomedical research. In particular, the primary goal of our
research is to study chemical and biological reactions in real-time at the
single-molecule level. The research
targets the most challenging questions in biology and aims to explore living
systems at the single-cell and single-molecule level. Ultimately, this research
will lead to the discovery of new chemical and biochemical concepts and mechanisms,
and the invention of novel technologies. Our research also aims to unravel
mysteries that presently prohibit us from completely understanding diseases
such as cancer and AIDS from their period of onset and development through
their diagnosis and treatment.
Current research projects include: (i) real-time study of
single-molecule dynamics and interactions for better understanding of molecular
self-assembly and rational design of bio-inspired molecular machinery, (ii)
real-time mapping of single ligand-receptor interactions on single living cells
for further understanding of signaling transduction pathways and rational
design of anti-cancer vaccines, (iii) real-time molecular probing of membrane
transport for better understanding of multidrug resistance, signaling pathways,
and cell-cell communication, (iv) high-throughput screening of tumor markers
using single-molecule analysis, (v) real-time study of effects of electric field and low-dose x-ray radiation on
cellular and subcellular function at single-living-cell
level to explore effective therapy, (vi) development of novel bionanomaterials, biotechnology and nanotechnology (e.g.,
biochip, nanoparticle probes, nanoparticle-optics, nanosensors,
living cell imaging), for biochemical and biomedical research, (vii) Study of
cytotoxicity and genotoxicity of nanomaterials,
(viii) Study of surface properties of single nanoparticles at the
single-molecule level, and (ix) electrochemiluminescence
studies of ligand-receptor interactions.
Project
Summary: click
Research Facilities and Resources
Postdoctoral Positions Available Immediately:
Postdoctoral Positions Available
Immediately:
Graduate Research Assistantship Available:
Research Group: (Group Photo) click
Principle
Investigator: Dr. X.
Nancy Xu (CV) click
Current
Group Members:
Research Scientists:
Dr. Tao Huang (
Postdoctoral
Fellows:
Dr. Ardi Vahedi (PhD,
University of
Illinois at Chicago)
Dr. Hongwu Xu (PhD,
SUNY
Binghamton)
Ph.D. Students (Biomedical
Sciences-Biological Chemistry or Chemistry):
Kerry Lee
Lauren M.
Browning
Pavan Kumar
Feng Ding
Pon Songkiatisak
Undergraduate Students:
Epi Perez
Kevin Kircheval
Kaleigh V. Wiley
Seth Warren
Clint-Jomar Bruno
Group Alumni:
Prakash D. Nallathamby (Graduated in May 2010)
Tanvi Desai
(Graduated in July 2008)
William Brownlow (Graduated in May 2006)
Sophia Kyriacou (Graduated in May 2003)
Jill E. Lowman (chemistry, Graduated
2008)
Elizabeth S Dupont (Outstanding graduate Senior
in chemistry; Graduated 2007)
Vassiliki Pravodelov (Outstanding graduate Senior in biochemistry;
Graduated 2007)
Renee A. Baker (biochemistry, Graduated in 2004)
Juan Pablo Rodríguez
M. (biochemistry,
Graduated 2003)
Chris Manno (physics, Graduated in May 2003)
Khalid Salaita (Chemistry, Graduated in 2001) (faculty
member in
Michelle Nowak (Outstanding graduate
Senior in biochemistry, Graduated 2000)
Bioanalytical/biochemistry:
Single
Nanoparticle Optics and Sensors (Featured
in NCI Alliance for Nanotechnology in Cancer)
Single-molecule Detection and Single Living Cell Imaging
Bionanotechnology and
Bionanomaterials (NIRT)
Bioelectrics
and Low-dose Radiation (MURI)
Updated
Publications & Presentations
Selected
Publications
Selected Presentations
Nearby Research Facilities and Institutes
Current
Research Support
Teaching
NIRT: Nanoscale Interdisciplinary Research Teams
Single-Molecule Journal Homepage
Nanosciences and Nanotechnology
We are interested in seeking collaborations
and welcome individuals joining our research team. Please email xhxu@odu.edu us with your comments!