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Dr. X. Nancy Xu
Professor in Chemistry and Biochemistry
Graduate Program Director of Ph.D. program in Biological Chemistry (2001-present)
Postdoctoral Fellow Ames Lab-USDOE/Dept. of
Chemistry, Iowa State University (1996-98)
Postdoctoral Fellow The
University of Texas at Austin (1993-95)
Ph.D. The University of
Mississippi (12/1992)
BS Xiamen University
(1989/85)
Chemistry and Biochemistry
Department Old
Dominion University, Norfolk, VA 23529
Ph.D. Program in Biomedical Sciences: Biological
Chemistry
Application
materials for graduate schools
News:
2009 Nanowerk Spotlight
2008 Nanotech Briefs Nano 50™ Innovator Award
2007
C&EN Highlight: In Vivo Imaging of Single Ag Nanoparticles, ACS Nano 1, 133 (2007) (Nano Movie, lab tour)
Nanotech Briefs Nano 50™ Awards in the Technology, ODU
News
2006
Single Nanoparticle
Optics Featured
in NCI Alliance for Nanotechnology in Cancer
Our Research Program in Bionanotechnology
Featured in 2006 University Video
NIH Support of Novel Nanoparticle
Assay Featured in ODU News and Virginian Pilot
Welcome to Dr. Xu
group: Laboratory of Bioanalytical/Biochemistry/Biophysics/Bionanotechnology/Bionanomaterial.
The central theme of our research program is the
development and application of cutting-edge bio- and nano-
technologies and ultrasensitive analytical
methodologies to address fundamental and practical questions in chemical,
biochemical and biomedical research. In
particular, the primary goal of our research is to study chemical and
biological reactions in real-time at the single-molecule level. The research targets the most challenging
questions in biology and aims to explore living systems at the single-cell and
single-molecule level. Ultimately, this research will lead to the discovery of
new chemical and biochemical concepts and mechanisms, and the invention of
novel technologies. Our research also aims to unravel mysteries that presently
prohibit us from completely understanding diseases such as cancer and AIDS from
their period of onset and development through their diagnosis and treatment.
Current research projects include: (i)
real-time study of single-molecule dynamics and interactions for better understanding
of molecular self-assembly and rational design of bio-inspired molecular
machinery, (ii) real-time mapping of single ligand-receptor
interactions on single living cells for further understanding of signaling
transduction pathways and rational design of anti-cancer vaccines, (iii)
real-time molecular probing of membrane transport for better understanding of multidrug resistance, signaling pathways, and cell-cell
communication, (iv) high-throughput screening of tumor markers using
single-molecule analysis, (v) real-time study
of effects of electric field and low-dose x-ray radiation on cellular and subcellular function at single-living-cell level to explore
effective therapy, (vi) development of novel bionanomaterials,
biotechnology and nanotechnology (e.g., biochip, nanoparticle
probes, nanoparticle-optics, nanosensors,
living cell imaging), for biochemical and biomedical research, (vii) Study of cytotoxicity and genotoxicity of nanomaterials, (viii) Study of surface properties of single
nanoparticles at the single-molecule level, and (ix) electrochemiluminescence studies of ligand-receptor
interactions.
Project Summary: click
Research
Facilities and Resources
Postdoctoral Positions Available Immediately:
Graduate Research Assitanship
Available:
Undergraduate Research Assistantship
Available:
Research Group: (Group Photo)
Principle
Investigator: Dr. X.
Nancy Xu (CV) click
Current
Group Members:
Research Scientists:
Dr. Tao Huang (PhD University of NC Chapel Hill)
Postdoctoral
Fellows:
Dr. Ardi Vahedi (PhD,
University of
Illinois at Chicago)
Dr. Hongwu Xu (PhD,
SUNY
Binghamton)
Ph.D. Students (Biomedical
Sciences-Biological Chemistry or Chemistry):
Prakash D. Nallathamby
Kerry Lee
Lauren M.
Browning
Pavan Kumar
Feng Ding
Venkat Moturi
Tanvi Desai (Graduated
in July 2008)
William Brownlow (Graduated in May 2006)
Sophia Kyriacou (Graduated in May 2003)
Undergraduate
Students:
Jill E. Lowman (chemistry, Graduated
2009)
Elizabeth S Dupont (Outstanding graduate Senior
in chemistry; Graduated 2007)
Vassiliki Pravodelov (Outstanding graduate Senior in biochemistry; Graduated
2007)
Renee A. Baker (biochemistry, Graduated in 2004)
Juan Pablo Rodríguez
M. (biochemistry,
Graduated 2003)
Chris Manno (physics, Graduated in May 2003)
Khalid Salaita (Chemistry, Graduated in 2001) (faculty
member in Emory U.)
Michelle Nowak (Outstanding graduate
Senior in biochemistry, Graduated 2000)
Bioanalytical/biochemistry:
Single
Nanoparticle Optics and Sensors (Featured
in NCI Alliance for Nanotechnology in Cancer)
Single-molecule Detection and Single Living Cell Imaging
Bionanotechnology and
Bionanomaterials (NIRT)
Bioelectrics
and Low-dose Radiation (MURI)
Updated Publications &
Presentations
Selected Publications
Selected Presentations
Nearby Research Facilities and Institutes
Current
Research Support
Teaching
NIRT: Nanoscale Interdisciplinary Research Teams
Single-Molecule Journal Homepage
Nanosciences and Nanotechnology
We are interested in seeking
collaborations and welcome individuals joining our research team. Please email xhxu@odu.edu us with your comments!