Roy Ogle

Ph.D. in Cell and Molecular Biology, University of Virginia, (1985)

B.A. in Biology, University of Virginia, (1972)

Research Interests

Regenerative medicine. Stem cell biology and therapy. Tissue engineering. Models for genetic disease. Biotechnology.

Articles

Neal, R. A., McClugage, S. G., Link, M. C., Sefcik, L. S., Ogle, R. and Botchwey, E. A. (2009). Laminin nanofiber meshes that mimic morphological properties and bioactivity of basement membranes.. Tissue engineering. Part C, Methods 15 (1) , pp. 11-21.

Petrie Aronin, C. E., Sefcik, L. S., Tholpady, S. S., Tholpady, A., Sadik, K. W., Macdonald, T. L., Peirce, S. M., Wamhoff, B. R., Lynch, K. R., Ogle, R. and Botchwey, E. A. (2010). FTY720 promotes local microvascular network formation and regeneration of cranial bone defects.. Tissue engineering. Part A 16 (6) , pp. 1801-9.

Petrie Aronin, C. E., Cooper, Jr, J. A., Sefcik, L. S., Tholpady, S. S., Ogle, R. and Botchwey, E. A. (2008). Osteogenic differentiation of dura mater stem cells cultured in vitro on three-dimensional porous scaffolds of poly(epsilon-caprolactone) fabricated via co-extrusion and gas foaming.. Acta biomaterialia 4 (5) , pp. 1187-97.

Sefcik, L. S., Neal, R. A., Kaszuba, S. N., Parker, A. M., Katz, A. J., Ogle, R. and Botchwey, E. A. (2008). Collagen nanofibres are a biomimetic substrate for the serum-free osteogenic differentiation of human adipose stem cells.. Journal of tissue engineering and regenerative medicine 2 (4) , pp. 210-20.

Gagan, J. R., Tholpady, S. S. and Ogle, R. (2007). Cellular dynamics and tissue interactions of the dura mater during head development.. Birth defects research. Part C, Embryo today : reviews 81 (4) , pp. 297-304.

Katz, A. J., Tholpady, A., Tholpady, S. S., Shang, H. and Ogle, R. (2005). Cell surface and transcriptional characterization of human adipose-derived adherent stromal (hADAS) cells.. Stem cells (Dayton, Ohio) 23 (3) , pp. 412-23.

Ogle, R., Tholpady, S. S., McGlynn, K. A. and Ogle, R. (2004). Regulation of cranial suture morphogenesis.. Cells, tissues, organs 176 (1-3) , pp. 54-66.

Tholpady, S. S., Katz, A. J. and Ogle, R. (2003). Mesenchymal stem cells from rat visceral fat exhibit multipotential differentiation in vitro.. The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology 272 (1) , pp. 398-402.

Opperman, L. A., Chhabra, A., Cho, R. W. and Ogle, R. (1999). Cranial suture obliteration is induced by removal of transforming growth factor (TGF)-beta 3 activity and prevented by removal of TGF-beta 2 activity from fetal rat calvaria in vitro.. Journal of craniofacial genetics and developmental biology 19 (3) , pp. 164-73.

Opperman, L. A., Passarelli, R. W., Morgan, E. P., Reintjes, M. and Ogle, R. (1995). Cranial sutures require tissue interactions with dura mater to resist osseous obliteration in vitro.. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 10 (12) , pp. 1978-87.

Opperman, L. A., Sweeney, T. M., Redmon, J., Persing, J. A. and Ogle, R. (1993). Tissue interactions with underlying dura mater inhibit osseous obliteration of developing cranial sutures.. Developmental dynamics : an official publication of the American Association of Anatomists 198 (4) , pp. 312-22.

Maghdouri-White, Y., Petrova, S., Sori, N., Polk, S., Wriggers, H. and Ogle, R. (2018). Electrospun silk-collagen scaffolds and BMP-13 for ligament and tendon repair and regeneration. Biomedical Physics & Engineering Express 4 (2) , pp. 1-14.

f, M. P.., Breathwaite, E., bu, A. A.., Varghese, F., Rodriguez, R. U.., Dutta, S., Semenov, I., Ogle, R., Huber, A., Tichy, A. M.., Chen, S. and Zemlin, C. (2017). Human placenta hydrogel reduces scarring in a rat model of cardiac ischemia and enhances cardiomyocyte and stem cell cultures. Acta Biomaterialia 52 , pp. 92-104.

Roberts, C. L., Chen, S. S., Murchison, A. C., Ogle, R., Francis, M. P., Ogle, R. C. and Sachs, P. (2017). Preferential Lineage-Specific Differentiation of Osteoblast-Derived Induced Pluripotent Stem Cells into Osteoprogenitors.. Stem cells international 2017 , pp. 1513281.

Ogle, R., Ogle, R., Johnson, G. D., Ogle, R., Bruno, R. and Sachs, P. (2016). Accessible bioprinting: adaptation of a low-cost 3D-printer for precise cell placement and stem cell differentiation.. Biofabrication 8 (2) , pp. 025017.

Das, A., Segar, C. E., Chu, Y., Wang, T. W., Lin, Y., Yang, C., Du , X., Ogle, R., Cui, Q. and Botchwey, E. A. (2015). Bioactive lipid coating of bone allografts directs engraftment and fate determination of bone marrow-derived cells in rat GFP chimeras.. Biomaterials 64 , pp. 98-107.

O'Connor, D. M., Naresh, N. K., Piras, B. A., Xu, Y., Smith, R. S., Epstein, F. H., Hossack, J. A., Ogle, R. and French, B. A. (2015). A novel cardiac muscle-derived biomaterial reduces dyskinesia and postinfarct left ventricular remodeling in a mouse model of myocardial infarction.. Physiological reports 3 (3).

O'Conner, D. M., Xu, Y., Naresh, N. K., Smith, R. S., Piras, B. A., Epstein, F. H., Hossack, J. A., Ogle, R. and French, B. A. (2013). A novel cardiac muscle-derived biomaterial reduces dyskinesia and post-infarct left ventricular remodeling in a mouse model of myocardial infarction. Circulation Research.

Tholpady, S. S., Stephan, S. J., Gross, B., Petrie-Aronin, C. E., Botchway, E. A., Nair, L. S., Park, S. S. and Ogle, R. (2013). Delivery of adipose stem cells in an injectable chitosan matrix for repair of calvarial defect. Craniofacial Surgery.

Huang, C. S., Das, A., Barker, D. A., Tholpady, S. S., Wang, T. W., Cui, Q., Ogle, R. and Botchwey, E. A. (2012). Local Delivery of FTY720 Accelerates Cranial Allograft Incorporation and Bone Formation. Cell Tiss. Res. 347 (3) , pp. 553-566.

Neal, R. A., Tholpady, S. S., Foley, P. L., Swami, N., Ogle, R. and Botchwey, E. A. (2011). Alignment and composition of laminin-polycaprolactone nanofiber blends enhance peripheral nerve regeneration.. Journal of biomedical materials research. Part A.

Tholpady, S. S. and Ogle, R. (2011). Expression of transforming growth factor-β-responsive smads in cranial suture development and closure.. The Journal of craniofacial surgery 22 (1) , pp. 324-8.

Stephan, S. J., Tholpady, S. S., Gross, B., Petrie-Aronin, C. E., Botchway, E. A., Nair, L. S., Ogle, R. and Park, S. S. (2010). Injectable tissue-engineered bone repair of a rat calvarial defect.. The Laryngoscope 120 (5) , pp. 895-901.

Petrie Aronin, C. E., Sadik, K. W., Lay, A. L., Rion, D. B., Tholpady, S. S., Ogle, R. and Botchwey, E. A. (2009). Comparative effects of scaffold pore size, pore volume, and total void volume on cranial bone healing patterns using microsphere-based scaffolds.. Journal of biomedical materials research. Part A 89 (3) , pp. 632-41.

Tholpady, S. S., Ogle, R. and Katz, A. J. (2009). Adipose stem cells and solid organ transplantation.. Current opinion in organ transplantation 14 (1) , pp. 51-5.

Tholpady, S. S., Freyman, T. F., Chachra, D. and Ogle, R. (2007). Application of cyclic tensional forces influence gene expression and sutural state of rat calvariae in vitro.. Plastic and reconstructive surgery 120 (3) , pp. 601-11; discussion 612-3.

Tholpady, S. S., Llull, R., Ogle, R., Rubin, J. P., Futrell, J. W. and Katz, A. J. (2006). Adipose tissue: stem cells and beyond.. Clinics in plastic surgery 33 (1) , pp. 55-62, vi.

Tholpady, S. S., Aojanepong, C., Llull, R., Jeong, J. H., Mason, A. C., Futrell, J. W., Ogle, R. and Katz, A. J. (2005). Morphology, growth and developmental plasticity of human adipocytes.. Annals of plastic surgery 54 (6) , pp. 651-6.

Abdelaal, M. M., Tholpady, S. S., Kessler, J. D., Morgan, R. F. and Ogle, R. (2004). BMP-9-transduced prefabricated muscular flaps for the treatment of bony defects.. The Journal of craniofacial surgery 15 (5) , pp. 736-41; discussion 742-4.

Tholpady, S. S., Abdelaal, M. M., Dufresne, C. R., Gampper, T. J., Lin, K. Y., Jane, Sr, J. A., Morgan, R. F. and Ogle, R. (2004). Aberrant bony vasculature associated with activating fibroblast growth factor receptor mutations accompanying Crouzon syndrome.. The Journal of craniofacial surgery 15 (3) , pp. 431-5; discussion 436-8.

MacRae, J. W., Tholpady, S. S., Ogle, R. and Morgan, R. F. (2004). Ex vivo fat graft preservation: effects and implications of cryopreservation.. Annals of plastic surgery 52 (3) , pp. 281-2; discussion 283.

Macrae, J. W., Tholpady, S. S., Katz, A. J., Gampper, T. G., Drake, D. B., Ogle, R. and Morgan, R. F. (2003). Human adipocyte viability testing: a new assay.. Aesthetic surgery journal / the American Society for Aesthetic Plastic surgery 23 (4) , pp. 265-9.

Mooney, M. P., Burrows, A. M., Smith, T. D., Losken, H. W., Opperman, L. A., Dechant, J., Kreithen, A. M., Kapucu, R., Cooper, G. M., Ogle, R. and Siegel, M. I. (2001). Correction of coronal suture synostosis using suture and dura mater allografts in rabbits with familial craniosynostosis.. The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 38 (3) , pp. 206-25.

Ogle, R. (2000). Craniofacial skeletal morphogenesis in vitro.. Methods in molecular biology (Clifton, N.J.) 136 , pp. 55-9.

Toung, J. S., Ogle, R., Morgan, R. F. and Lindsey, W. H. (1999). Repair of a rodent nasal critical-size osseous defect with osteoblast augmented collagen gel.. The Laryngoscope 109 (10) , pp. 1580-4.

Tholpady, S. S., Schlosser, R., Spotnitz, W., Ogle, R. and Lindsey, W. H. (1999). Repair of an osseous facial critical-size defect using augmented fibrin sealant.. The Laryngoscope 109 (10) , pp. 1585-8.

Toung, J. S., Ogle, R., Morgan, R. F. and Lindsey, W. H. (1999). Insulinlike growth factor 1- and 2-augmented collagen gel repair of facial osseous defects.. Archives of otolaryngology--head & neck surgery 125 (4) , pp. 451-5.

Toung, J. S., Griffin, A., Ogle, R. and Lindsey, W. H. (1998). Repair of nasal defects using collagen gels containing insulin-like growth factor 1.. The Laryngoscope 108 (11 Pt 1) , pp. 1654-8.

Opperman, L. A., Chhabra, A., Nolen, A. A., Bao, Y. and Ogle, R. (1998). Dura mater maintains rat cranial sutures in vitro by regulating suture cell proliferation and collagen production.. Journal of craniofacial genetics and developmental biology 18 (3) , pp. 150-8.

Lin, K. Y., Nolen, A. A., Gampper, T. J., Jane, J. A., Opperman, L. A. and Ogle, R. (1997). Elevated levels of transforming growth factors beta 2 and beta 3 in lambdoid sutures from children with persistent plagiocephaly.. The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 34 (4) , pp. 331-7.

Chen, L., Shick, V., Matter, M. L., Laurie, S. M., Ogle, R. and Laurie, G. W. (1997). Laminin E8 alveolarization site: heparin sensitivity, cell surface receptors, and role in cell spreading.. The American journal of physiology 272 (3 Pt 1) , pp. L494-503.

Opperman, L. A., Nolen, A. A. and Ogle, R. (1997). TGF-beta 1, TGF-beta 2, and TGF-beta 3 exhibit distinct patterns of expression during cranial suture formation and obliteration in vivo and in vitro.. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 12 (3) , pp. 301-10.

Valente, P., Noonan, D. M., Ogle, R. and Albini, A. (1996). Altered production of laminin and nidogen by high and low metastatic variants of murine melanoma cells.. Oncology research 8 (3) , pp. 131-8.

Lindsey, W. H., Ogle, R., Morgan, R. F., Cantrell, R. W. and Sweeney, T. M. (1996). Nasal reconstruction using an osteoconductive collagen gel matrix.. Archives of otolaryngology--head & neck surgery 122 (1) , pp. 37-40.

Brees, D. K.., Ogle, R. and Williams, Jr., J. C.. (1995). Laminin and Fibronectin Content of Mouse Glomerular and Tubular Basement Membrane. Kidney and Blood Pressure Research 18 (1) , pp. 1-11.

Ricciardelli, E. J., Persing, J. A., Romano, J. A., Morgan, R. F. and Ogle, R. (1995). A rapid in vitro assay of cellular chemomigration in an epithelial carcinoma cell line.. Plastic and reconstructive surgery 96 (7) , pp. 1689-93.

Sweeney, T. M., Opperman, L. A., Persing, J. A. and Ogle, R. (1995). Repair of critical size rat calvarial defects using extracellular matrix protein gels.. Journal of neurosurgery 83 (4) , pp. 710-5.

Brees, D. K., Ogle, R. and Williams, Jr, J. C. (1995). Laminin and fibronectin content of mouse glomerular and tubular basement membrane.. Renal physiology and biochemistry 18 (1) , pp. 1-11.

Opperman, L. A., Persing, J. A., Sheen, R. and Ogle, R. (1994). In the absence of periosteum, transplanted fetal and neonatal rat coronal sutures resist osseous obliteration.. The Journal of craniofacial surgery 5 (5) , pp. 327-32.

Drake, D. B., Persing, J. A., Berman, D. E. and Ogle, R. (1993). Calvarial deformity regeneration following subtotal craniectomy for craniosynostosis: a case report and theoretical implications.. The Journal of craniofacial surgery 4 (2) , pp. 85-9; discussion 90.

Sweeney, T. M., Ogle, R. and Little, C. D. (1990). Laminin potentiates differentiation of PCC4uva embryonal carcinoma into neurons.. Journal of cell science 97 ( Pt 1) , pp. 23-31.

Ogle, R., Potts, A. J., Yacoe, M. and Little, C. D. (1989). Embryonic chicken fibroblast collagen binding proteins: distribution, role in substratum adhesion, and relationship to integrins.. Journal of cell science 94 ( Pt 2) , pp. 361-9.

Albini, A., Aukerman, S. L., Ogle, R., Noonan, D. M., Fridman, R., Martin, G. and Fidler, I. J. (1989). The in vitro invasiveness and interactions with laminin of K-1735 melanoma cells. Evidence for different laminin-binding affinities in high and low metastatic variants.. Clinical & experimental metastasis 7 (4) , pp. 437-51.

Ogle, R. and Little, C. D.. (1989). Collagen binding proteins derived from the embryonic fibroblast cell surface recognize arginine-glycine-aspartic acid. Bioscience Reports 9 (3) , pp. 329-340.

Ogle, R. and Little, C. D. (1989). Collagen binding proteins derived from the embryonic fibroblast cell surface recognize arginine-glycine-aspartic acid.. Bioscience reports 9 (3) , pp. 329-40.

Davis, L. A., Ogle, R. and Little, C. D. (1989). Embryonic heart mesenchymal cell migration in laminin.. Developmental biology 133 (1) , pp. 37-43.

Kleinman, H. K., Ogle, R., Cannon, F. B., Little, C. D., Sweeney, T. M. and Luckenbill-Edds, L. (1988). Laminin receptors for neurite formation. Proc. Natl. Acad. Sci. USA 85 (4) , pp. 1282-1286.

Johnson, B. R., Merrill, C. L., Ogle, R. and Atema, J. (1988). Response properties of primary olfactory neurons from the lobster: Tuning of hydroxy-proline sensitive cells. J. Comp. Phys. 162 , pp. 201-211.

Amero, S. A., Montoya, V. L., Murdoch, W. L., Ogle, R., Keating, J. L. and Grainger, R. M. (1988). The characterization of ribosomal RNA gene chromatin from Physarum polycephalum.. The Journal of biological chemistry 263 (22) , pp. 10734-44.

Amero, S. A., Ogle, R., Keating, J. L., Montoya, V. L., Murdoch, W. L. and Grainger, R. M. (1988). The purification of ribosomal RNA gene chromatin from Physarum polycephalum.. The Journal of biological chemistry 263 (22) , pp. 10725-33.

Kleinman, H. K., Ogle, R., Cannon, F. B., Little, C. D., Sweeney, T. M. and Luckenbill-Edds, L. (1988). Laminin receptors for neurite formation.. Proceedings of the National Academy of Sciences of the United States of America 85 (4) , pp. 1282-6.

Graf, J., Ogle, R., Robey, F. A., Sasaki, M., Martin, G., Yamada, Y. and Kleinman, H. K. (1987). A pentapeptide from the laminin B1 chain mediates cell adhesion and binds the 67,000 laminin receptor.. Biochemistry 26 (22) , pp. 6896-900.

Kleinman, H. K., Graf, J., Iwamoto, Y., Kitten, G. T., Ogle, R., Sasaki, M., Yamada, Y., Martin, G. and Luckenbill-Edds, L. (1987). Role of basement membranes in cell differentiation.. Annals of the New York Academy of Sciences 513 , pp. 134-45.

Ogle, R., Piguet, D. M. and Little, C. D. (1986). Collagen binding proteins associated with the chicken embryonic cell surface. Progress in Clinical & Biological Research 217B , pp. 173-176.

Ogle, R., Piguet, D. M. and Little, C. D. (1986). Collagen binding proteins associated with the chicken embryonic cell surface.. Progress in clinical and biological research 217B , pp. 173-6.

Ogle, R., Sussman, M. D., Mabie, G., Hubbard, S. and Balian, G. (1983). Structure and biosynthesis of collagen in skeletal tissues. Connect. Tiss. Res. 11 , pp. 234-235.

Grainger, R. M.. and Ogle, R. (1978). Chromatin structure of the ribosomal RNA genes in Physarum polycephalum. Chromosoma 65 (2) , pp. 115-126.

Schartz, E. R., Ogle, R. and Thompson, R. C. (1974). Aryl sulfatase activities in normal and pathologic human articular cartilage.. Arthritis and rheumatism 17 (4) , pp. 455-67.

Presentations

Ogle, R. (February , 2014). Regenerative medicine and biotechnology. Oral Presentation Hampton University.

Ogle, R., Roberts, C., Ogle, R. A., Chen, S. and Sachs, P. (June , 2013). Derivation, differentiation, and growth of definitive endodermal cells from reprogrammed donor fibroblasts Oral Presentation ISSCR International Meeting Boston, MA.

Ogle, R. (October 2, 2012). Breakthroughs and opportunities in the science and commercializatio of regenerative medicine Oral Presentation Bioscience Luncheon Richmond, VA.

Ogle, R., Roberts, C. and Ogle, R. A. (November , 2011). The Adipose Tissue Extracellular Matrix Role in Adipose Stem Cell Differentiation Oral Presentation Miami, FL.

Ogle, R., O'Connor, D. M., Xu, Y., Naresh, N. K., Smith, R. S., Piras, B. A., Epstein, F. H., Hossack, J. A. and French, B. A. (October , 2011). A novel cardiac muscle-derived biomaterial reduces dyskinesia and pos-infarct left ventricular remodeling in a mouse model of myocardial infarction Oral Presentation Orlando, FL.

Ogle, R. (September 28, 2010). Advances in Stem Cell Therapies Oral Presentation Williamsburg, VA.

Ogle, R. (July 29, 2010). Recent Advances in Oral Regenerative Medicine Oral Presentation Point Clear, Alabama.

Ogle, R. (June 15, 2010). Emerging Synergies in Stem Cell Therapy and Organ Transplantation Oral Presentation 27th Annual Meeting Baltimore, MD.

Ogle, R., Stephan, S. R., Tholpady, S. S. and Park, S. ( 2009). Repair of a facial critical size defect using injectable chitosan-alginate scaffolding for the delivery of tissue engineered bone Oral Presentation .

Ogle, R., Yang, Y., Nguyen, L., Rush, M., Botchwey, E. A. and Katz, A. J. (October 15, 2009). Novel Electrospun Polymer Scaffolds with Microencapsulated Human ASCs for Tissue Oral Presentation 7th Annual Meeting Daegu, Korea.

Ogle, R. (November 7, 2008). Regenerative Medicine: the Time is Now! Oral Presentation VA Beach, VA.

Ogle, R., Petrie, C. E., Sefcik, L. A., Macdonald, T., Lynch, K. and Botchwey, E. A. (September , 2008). Selective Activation of Sphingosine 1-Phosphate (S1P) Receptors Enhances Vessel Stabilization and Bone Regeneration in a Cranial Defect Model Oral Presentation Atlanta, GA.

Ogle, R., Sefcik, L., Parker, A., Katz, A. and Botchwey, E. A. (September , 2007). 3D collagen nanofibers enhance serum free osteogenic differentiation of adipose-derived stem cells. Oral Presentation Annual Fall Meeting Los Angeles, CA.

Ogle, R., Neal, R., McCluggage, T. and Botchwey, E. A. (September , 2007). Biomimetic laminin nanofiber scaffolds for peripheral nerve repair Oral Presentation Annual Fall Meeting Los Angeles, CA.

Ogle, R., Petrie, C. E., Tholpady, S. S. and Botchwey, E. A. (September , 2007). Controlled release of sphingosphine-1-phosphate from PLGA scaffolds to aid in cranial bone repair Oral Presentation Annual Fall Meeting Los Angeles, CA.

Ogle, R., Petrie, C. E., Sadik, K. W., Tholpady, S. S. and Botchwey, E. A. (September , 2007). In vivo evaluation of PLGA scaffolds varying in size and density in a cranial defect. Oral Presentation Annual Fall Meeting Los Angeles, CA.

Ogle, R., Petrie, C. E., Tholpady, S. S. and Botchwey, E. A. (September , 2007). PLGA submicron meshes seeded with primary stem cells used to heal cranial defects Oral Presentation Annual Fall Meeting Los Angeles, CA.

Ogle, R., Tholpady, S. S., Sadik, K. W., Petrie, C. E., Morgan, R. F. and Botchwey, E. A. (June , 2007). Pore Size Determines Osteogenic Capacity of PLGA Constructs In Vivo Oral Presentation 52 Annual Meeting of Plastic Surgery Research Council Stanford, CA.

Ogle, R., Tholpady, S. S., Tholpady, A. and Morgan, R. F. (June , 2007). Differentiation of Adipose Stem Cells (ASCs) to Orthoclastic Lineage Lecture 52nd Annual Meeting of Plastic Surgery Research Council Stanford, CA.

Ogle, R., Tholpady, S. S., Sadik, K. W., Petrie, C. E., Morgan, R. F. and Botchwey, E. A. (June , 2007). Differentiative and Proliferative Capacity of Adipose and Dural Stem Cells Cultured on PLGA Microspheres Oral Presentation 52nd Annual Meeting of Plastic Surgery Research Council Stanford, CA.

Ogle, R. (May 4, 2007). Biomimetic Scaffolds and Stem Cells for Organ and Glandular Engineering Oral Presentation Department of Medicine Research Day Charlottesville, VA.

Ogle, R. (March 29, 2007). The New Science and Medicine of Stem Cells Oral Presentation Staunton, VA.

Ogle, R., Ogle, R., Tholpady, A., Sefcik, L. and Botchwey, E. (August , 2006). Production of Osteoclasts from human Adipose Tissue under Chemically-Defined Conditions Oral Presentation .

Ogle, R., Petrie, C. and Botchwey, E. (August , 2006). Prolifertive Capacity and Osteogenic Differentiation Behavior of Novel Dura Stem Cells Oral Presentation .

Ogle, R., Sefcik, L. S., Petrie, C. E., Tholpady, S. S., Cooper, J. A., Katz, A. J. and Botchwey, E. A. (September , 2005). Osteogenic Differentiation of Human Adipose-Derived Stem Cells (ASCs) Oral Presentation Annual Fall Meeting Baltimore, MD.

Ogle, R., Petrie, C. E. and Botchwey, E. A. (September , 2005). Proliferative Capacity and osteogenic Differentiation Behavior of Novel Dura Stem Cells Oral Presentation Annual Fall Meeting Baltimore, MD.

Ogle, R., Botchwey, E. A., Petrie, C. E., Tholpady, S. S. and Ogle, R. A. (September , 2005). Novel Multipotent Progenitor Cells for Bone Tissue Repair Oral Presentation Annual Meeting Baltimore, MD.

Ogle, R., Botchwey, E. A., Sefcik, L. S., Petrie, C. E., Tholpady, S. S. and Ogle, R. A. (September , 2005). Osteogenic Differentiation of Human Adipose-Derived Stem Cell: Effects of Initial Plating Density Oral Presentation Annual Meeting Baltimore, MD.

Ogle, R., Tholpady, A., Tholpady, S. S. and Katz, A. J. (September 13, 2005). Differentation of ASCs to Osteoclasts in Vivo and in Vitro Oral Presentation (IFATS) 3rd international Meeting Charlottesville, VA.

Ogle, R. (September 13, 2005). Bone and Cartilage Differentiation and Tissue Engineering Oral Presentation 3rd International Meeting Charlottesville, VA.

Ogle, R. and Tholpady, S. S. (September 12, 2005). Neural Differentiative Response in ASCs Oral Presentation 3rd Internationa Meeting Charlottesville, VA.

Ogle, R., Petrie, C., Sefcik, L., Tholpady, S., Katz, A. and Botchwey, E. (June , 2005). Osteogenic Differentiation of Human Adipose-Derived Stem Cells: The Effects of Initial Cell Plating Density Oral Presentation Bioengineering Conference Vail, CO.

Ogle, R., Petrie, C. and Botchwey, E. (June , 2005). Novel Progenitor Cells for Use in Bone Tissue Repair American Society of Mechanical Engineering Summer Bioengineering Conference Oral Presentation Bioenginnering Conference Vail, CO.

Ogle, R. (May 25, 2005). The Future of Stem Cell Therapy in the US Oral Presentation Rochester, MI.

Ogle, R., Petrie, C., Tholpady, S. and Botchwey, E. (April , 2005). Novel Multipotent Progenitor Cells for Bone Tissue Repair. Oral Presentation Annual Meeting Memphis, TN.

Ogle, R., Petrie, C., Tholpady, S. S. and Botchwey, E. (October , 2004). Tissue Engineered Bone: 3-D Bone Cell Co-Culture with Vascular Endothelial Cells. Oral Presentation Annual Meeting Philadelphia, PA.

Ogle, R. (October , 2004). Bone Regeneration with Human Adipose-derived Stem Cells. Oral Presentation Pittsburgh, PA.

Ogle, R. and Tholpady, S. S. (April , 2003). TGF-beta Signaling intermediates in the Maintenance of Cranial Sutures. Oral Presentation 48th Annual Meeting of the Plasic Surgery Research Council Las Vegas, NV.

Ogle, R., Tholpady, S. S., Kessler, J. D. and Chopra, C. (April , 2003). Cakvarial Osteogrogenitor Cells Exhibit Differential Cellular Responses to Fibroblast Growth Factors. Oral Presentation 48th Annual Meeting of the Plastic Surgery Research Council Las Vegas, NV.

Ogle, R., Tholpady, S. S., Freyman, T. F. and Chachra, D. (April , 2003). Tensional Forces Induce Changes in Suture Patency and Cell Behavior. Oral Presentation 48th Annual Meeting of the Plastic Surgery Research Council Las Vegas, NV.

Ogle, R., Tholpady, S. S., Lin, K., DeFresne, C., Gampper, T. J., Jane, Sr., J. A. and Abdelaal, M. (April , 2003). Aberrant Bony Vasculature Associated with FGFR Mutations in Crouzon Syndrome. Oral Presentation 48th Annual Meeting of the PSRC Las Vegas, NV.

Ogle, R. (March , 2003). Regulation of Cranial Suture Morphogenesis Oral Presentation Joint Meeting of American, Canadian and International Associations for Dental Research San Antonio.

Ogle, R., Hahn, J. S., Tholpady, S. S. and Lindsay, W. A. (January , 2003). The Use of Osteoblast-Enhanced Collagen Sponge in the Repair of Critical-Size Defects in Rodent Nasal Bones. Lecture Naples, FL.

Ogle, R., MacRae, J. W., Tholpady, S. S., Gampper, T. J., Katz, A. J. and Morgan, R. F. (June , 2002). Human Adipocyte Viability Testing Oral Presentation 25th Annual Meeting Southeastern Society of Plastic & Reconstructive Surgeons Hilton Head.

Ogle, R., MacRae, J. W., Tholpady, S. S., Gampper, T. J., Katz, A. J. and Morgan, R. F. (May , 2002). Human Adipocyte Viability Testing Oral Presentation Resident Competition .

Ogle, R., MacRae, J. W., Tholpady, S. S., Gampper, T. J. and Morgan, R. F. (April , 2002). Human Adipocyte Viability in Fat Grafting. Oral Presentation Las Vegas, NV.

Ogle, R., Abdelaal, M., Tholpady, S. S., Helm, G., Morgan, R. F. and Katz, A. J. (April 17, 2002). Osteoblasts Differentiate from Human Fat Derived Stem Cells when Infected with a BMP-9 Expressing Adenovirus. Oral Presentation 47th Annual Meeting of the Plastic Surgery Research Council Boston, MA.

Ogle, R., Tholpady, S. S. and Lindsey, W. H. ( 2000). A rabbit auricular cartilage critical size defect model-healing with fibrin. Lecture Eighth Internatioal Symposium on Biomaterials Kamuela, Hawaii.

Ogle, R., Toung, J. S. and Lindsey, W. H. (May 15, 2000). Growth factor augmented zyderm II prolongs retention of soft tissue enhancements. Oral Presentation 103rd Annual Meeting of the Triological Society Orlando, FL.

Ogle, R., Toung, J. S. and Lindsey, W. H. (May 15, 2000). Use of bovine injectable collagen and three-dimensional type II gels in the repair of osseous nasal defects. Oral Presentation 103rd Annual Meeting of the Triological Society Orlando, FL.

Ogle, R., Tholpady, S. S., Schlosser, R., London, S. D. and Lindsey, W. H. ( 1999). A rabbit auricular cartilage critical size defect model. Lecture Eight International Symposium on Facial Plastic Surgery Palm Springs, CA.

Ogle, R. (April 29, 1999). Mechanisms of premature suture obliteration Lecture Eigth Annual Lars Leksell Lecture Series Charlottesville, VA.

Ogle, R. (April 15, 1999). Growth factor regulation of cranial suture morphogenesis and fusion. Lecture Scottsdale, AZ.

Ogle, R., London, S. D., Toung, J. S., Tholpady, S. S. and Lindsey, W. H. (January 15, 1999). Proliferation and expression of fibroblast growth factor receptors 1, 2, and 3 by auricular and septal chondrocytes Lecture New Orleans, LA.

Ogle, R., Toung, J. S. and Lindsey, W. H. (January 15, 1999). Repair of a rodent nasal critical size osseous defect with osteoblast-augmented collagen gel. Lecture New Orleans, LA.

Ogle, R., Tholpady, S. S., Schlosser, R., Spotnitz, W. and Lindsey, W. H. (January 15, 1999). Repair of osseous facial critical size defect using augmented fibrin. Lecture New Orldeans, LA.

Ogle, R., Mooney, M. P., Siegel, M. I., Losken, H. W., Burrows, A. M., Smith, T. D., Cooper, G. M., Dechant, J. J., Poisson, E., Sciote, J. J. and Opperman, L. A. (November 22, 1998). Characterization of a strain of rabbits with familial craniosynostosis. Oral Presentation "Toward a Molecular understanding of Craniofacial Morphogenesis- An International Symposium Bethesda, MD.

Ogle, R. (November 22, 1998). Fibroblast growth factor signaling during cranial suture morphogenesis. Oral Presentation Toward a Molecular Understanding of Craniofacial Morphogenesis - An International Symposium Bethesda, MD.

Ogle, R., Toung, J. S. and Lindsey, W. H. (June 18, 1998). Insulin-like growth factor 1 and 2 augmented collagen gel repair of facial osseous defects Lecture Seventh International Symposium on Facial Plastic Surgery Orlando, FL.

Ogle, R., Toung, J. S., Griffen, A. S. and Lindsey, W. H. (January , 1998). Repair of facial critical size defects using insulin-like growth factor 1 in a rodent model. Lecture Orlando, FL.

Ogle, R., Gamper, T. J., Opperman, L. A. and Edgerton, M. T. (September 17, 1997). Morphologic changes in the rat neonatal coronal suture with microinjection of IGF and neutralizinig antibodies to TGF-beta-3. Lecture Seventh Int. Congr. Craniofac. Surg. Santa Fe, NM.

Ogle, R., Mooney, M. P., Opperman, L. A., Losken, H. W., Smith, T. D., Dechant, J., Kreithen, A. M., Kapucu, R. and Siegel, M. I. (April , 1997). Biosurgical manipulation of the coronal suture and dura in rabbits with naturally occurring craniosynostosis. Oral Presentation 26th Annual Meeting of the International Assoc. for Dental Research Orlando, FL.

Ogle, R., Mooney, M. P., Opperman, L. A., Losken, H. W., Smith, T. D., Dechant, J., Kreithen, A. M., Kapucu, R. and Siegel, M. I. (April , 1997). Biosurgical manipulation of the coronal suture and dura in rabbits with naturally occurring craniosynostosis. Oral Presentation 54th Annual Meeting of the American Cleft Palate-Craniofacial Assoc. New Orleans, LA.

Ogle, R., Chhabra, A. N., Nolen, A. A., Opperman, L. A. and Jane, J. A. (April 16, 1997). TGF betas 2 and 3 play opposing roles in regulating rat cranial vault suture morphogenesis. Lecture 1997 Annual Meeting Denver, CO.

Ogle, R., Opperman, L. A., Nolen, A. A., Brooke, B. S. and Chhabra, A. (June , 1996). A role for transforming growth factor (TGF) beta 3 in preventing osseous obliteration of rat cranial vault sutures in vitro. Lecture 41st Annual Meetingof Plast. Surg. Res. Council St. Louis, MO.

Ogle, R., Opperman, L. A., Brooke, B. S., Chhabra, A. N. and Nolen, A. A. (April 24, 1996). Expression of TGF beta 1,2,3, by dura mater: role in regulating cranial suture morphogenesis. Lecture 53rd Annual Meeting Cleft Palate-Craniofacial Assoc. San Diego, CA.

Ogle, R., Neeley, J., Dietz, N., Romano, J. A. and Hens, M. D. (March 30, 1996). Regulation of integrin subunit expression in murine melanoma cells. Lecture Amer. Cancer Soc. of Virginia State Meeting Norfolk, VA.

Ogle, R., Lin, K., Opperman, L. A., Nolan, A. A. and Jane, J. A. (October 24, 1995). Surgical approach to posterior skull deformitites. Lecture Sixth Int. Cong. Craniofac. Surg. St. Tropez, FRANCE.

Ogle, R., Kittredge, B. W., O'Shea, J., Urch, S. and Sweeney, T. M. (February 13, 1995). Rapid bone regeneration induced by IGF-1 in type 1 collagen gels. Lecture 41st Annual Meeting of Orthop. Res. Society Orlando, FL.

Ogle, R., Urch, S., Kittredge, B., Brooke, B., O'Shea, J., Liu, G. and Sweeney, T. M. (February 13, 1995). Repair of rat femoral defects with collagen Type 1 occurs through endochondral mechanisms. Lecture 41st Annual Meeting of Orthop. Res. Society Orlando, FL.

Ogle, R., Sweeney, T. M., Helm, G. and Jane, J. A. (February 13, 1995). Type 1 collagen gel improves spinal fusion using autograft and demineralized bone matrix in a canine model. Lecture 41st Annual Meeting of Orthop. Res. Society Orlando, FL.

Ogle, R., Lindsey, W. H., Morgan, R. F. and Cantrell, R. W. (September , 1994). Nasal reconstruction using an osteoconductive collagen gel matrix. Lecture Annual Meeting of American Academy of Facial Plastic and Rec. Surg. San Diego, CA.

Ogle, R., Opperman, L. A. and Passarelli, R. (June 4, 1994). Soluble heparin binding factors arising in the dura mater are required for calvarial suture morphogenesis. Lecture 39 Annual Meeting Ann Arbor, Michigan.

Ogle, R., Gamper, T. J., Morgan, R. F., Edgerton, M. T. and Opperman, L. A. (June 4, 1994). The role of the extracellular matrix and basement membrane in cogenital vascular lesions. Lecture 39th Annual Meeting Ann Arbor, Michigan.

Ogle, R., Opperman, L. A., Passarelli, R., Lin, K. and Walford, T. (May 18, 1994). Calvarial suture patency requires soluble heparin-binding factors arising from the dura meter. Lecture 51st Annual Meeting Toronto.

Ogle, R., Gampper, T. J., Morgan, R. F., Edgerton, M. T. and Opperman, L. A. (May 4, 1994). The role of the extracellular matrix and basement membrane in congenital vascular lesions. Lecture Annual Meeting St. Louis, MO.

Ogle, R., Sweeney, T. M., Chhabra, A., Brooke, B. and Opperman, L. A. (February 21, 1994). Type 1 collagen gels mediate total repair of critical size bone defect through intramembranous ossification. Lecture 40th Annual Meeting of Orthop Res. Society New Orleans.

Ogle, R., Sweeney, T. M. and Brooke, B. (February 21, 1994). Quantitative analysis of bone repair using three-dimensional reconstruction of computed tomography. Lecture 40th Annual Meeting of Orthop. Res. Society New Orleans.

Ogle, R., Sweeney, T. M., Lindsey, W. H., Cantrell, R. W. and Morgan, R. F. (November , 1993). Osteoconductive gel for nasal dorsum reconstruction Oral Presentation Breckenridge, CO.

Ogle, R., Opperman, L. A. and Persing, J. A. (October 24, 1993). The critical role of the dura mater in maintaining patency of cranial sutures. Lecture Oaxaca, Mexico.

Ogle, R., Gampper, T. J. and Opperman, R. F. (September , 1993). Characterization of the extracellular matrix and basement membrane of hemangiomas. Lecture New Orleans.

Ogle, R., Romano, J., Perman, B. and Hens, M. D. (April 28, 1993). Monoclonal antibody to integrins indicates metastatic potential of primary melanomas. Lecture 38th Annual Meeting Houston, TX.

Ogle, R., Passarelli, R., Reintjes, M., Lin, K. and Opperman, L. A. (April 28, 1993). The dura mater expresses soluble factors, which maintain coronal suture integrity. Lecture 38th Annual Meeting Houston, TX.

Ogle, R., Opperman, L. A., Sweeney, T. M., Sheen, R., Morgan, E. P. and Persing, J. A. (April 28, 1993). Tissue interactions with dura mater regulate coronal suture morphogenesis and patency. Lecture 38th Annual meeting Houston, TX.

Ogle, R., Sweeney, T. M. and Opperman, L. A. (April 28, 1993). Total repair of non-healing cranial osseous defects by engineered osteogenic grafts. Lecture 38th Annual Meeting Houston, Texas.

Ogle, R., Sweeney, T. M., Opperman, L. A. and Persing, J. A. (March 29, 1993). Mechanisms of repair of critical size defects by transplantation of osteogenic cells in collagen gels Oral Presentation Breckenridge, CO.

Ogle, R., Ricciardelli, E., Romano, J. and Morgan, R. F. (February , 1993). An In Vitro Assay for Squamous Cell Carcinoma Lecture 35th Annual University Surgical Resident's Conference Seattle, WA.

Ogle, R., Sweeney, T. M., Opperman, L. A. and Persing, J. A. (February 15, 1993). Transplanted osteoblasts in type 1 collagen gels repair of critical size rat calvarial defects. Lecture 39th Annual Meeting of Orthop. San Francisco, CA.

Ogle, R., Ricciardelli, E., Persing, J. A., Romano, J. and Morgan, R. F. (November , 1992). An In Vitro Assay for Squamous Cell Carcinoma Lecture Los Angeles, CA.

Ogle, R., Wang, D., Morgan, R. F., Persing, J. A. and Edgerton, M. T. (April , 1992). Characterization of basement membranes and endothelial cells of prolifertive hemangiomas Lecture Toronto.

Ogle, R., Persing, J. A., Opperman, L. A., Sweeney, T. M. and Amiss, L. R. (April , 1992). Regulation of cranial suture morphogenesis by dura mater. Lecture San Francisco, CA.

Ogle, R. (April , 1991). Differences in integrin expression correlate wih the metastatic phenotype in murine melanoma cells Oral Presentation Charlottesville, VA.

Ogle, R. and Hens, M. (March , 1990). Differential Expression of collagen IV binding integrins by murine melanoma cells. Lecture Bethesda, MD.

Ogle, R. (January , 1989). Receptors for collagen type IV. Oral Presentation San Francisco, CA.

Ogle, R. (December , 1986). Immunostaining and immunochemical studies of a 56 Kd collagen binding protein in embryonic chick fibroblasts. Oral Presentation Washington, DC.

Ogle, R., Yacoe, M., Piguet, D. and Little, C. (April , 1986). The role of collagen binding proteins during embryogenesis. Lecture Reno, NV.

Ogle, R. and Little, C. (November , 1985). Collagen binding proteins are involved in substrate adhesion. Lecture Atalanta, GA.

Ogle, R. (October , 1985). Other Seminar, Laboratory of Developmental Biology Bethesda, MD.

Ogle, R. and Little, C. (August , 1985). Interactions of embryonic mesenchymal cell surface proteins with collagen. Oral Presentation Los Angeles, CA.

Ogle, R. and Little, C. (March , 1984). Isolation and characterization of collagen binding proteins from chicken embryonic cells. Lecture Woods Hole, MA.

Ogle, R., Sussman, M. D. and Balian, G. (March , 1983). Structure and distribution of collagen types in cartilaginous tissues Lecture Bethesda, MD.

• 2014: Entsminger Fellow, Old Dominion University
• 2003: Keynote Speaker, Joint Meeting of American, Canadian and International Associations for Dental Research, San Antonio
• 1997: Board of Scientific Counselors, National Space Biomedical Research institute
• 1994: Oral Biology and Medicine Study Section 2, 1994-2000, NIH
• 1994: NASA Peer Review and Site Visit Panel, NASA
• 1968: Philip Francis du Pont Scholar, University of Virginia