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Roy Ogle

  • Roy Ogle
  • Professor & Chair
  • Medical Diagnostic & Translational Sciences
  • 2118 Health Sciences Bldg
  • Norfolk, VA 23529
  • 757-683-3589
  • rogle@odu.edu
  • Grew up in Bristol, VA. Educated and employed by the University of Virgina for over 40 years.
  • Education

    University of Virginia, 1985
    Major: Cell and Molecular Biology
    Degree: Ph. D.
    University of Virginia, 1972
    Major: Biology
    Degree: B.A.
  • Research Interests

    Regenerative medicine. Stem cell biology and therapy. Tissue engineering. Models for genetic disease. Biotechnology.
  • 2014: Entsminger Fellow, Old Dominion University
  • 2003: Keynote Speaker, Joint Meeting of American, Canadian and International Associations for Dental Research, San Antonio
  • 1997: Board of Scientific Counselors, National Space Biomedical Research institute
  • 1994: Oral Biology and Medicine Study Section 2, 1994-2000, NIH
  • 1994: NASA Peer Review and Site Visit Panel, NASA
  • 1968: Philip Francis du Pont Scholar, University of Virginia
  • Contracts, Grants and Sponsored Research

    Therapeutic S1P Drug Targets for Cranial Bone Repair
    Sponsoring Organization: NIH, NIAMS
    Date: 2009 - 2014
    Awarding Organization: Federal
    Investigators:Ogle, R.; Botchwey,; Cottler-Peirce, H.
    Development of Human Adipose Stem Cells and Anti-inflammatory Drugs in ALS Therapy.
    Sponsoring Organization: Virginia Gentleman Foundation
    Date: 2010 - 2013
    Awarding Organization: Federal
    Investigators:Ogle, R.; Godfrey,
    Drug Recruitment of endogenous Stem Cells during Cranial Bone Repair
    Sponsoring Organization: DOD
    Date: 2010 - 2013
    Awarding Organization: Federal
    Investigators:Ogle, R.; Botchway,
    Peer Review orthopedic research program, Novel Bioactive Coatings to Improve Allograft Incorporation
    Sponsoring Organization: DOD
    Date: 2010 - 2013
    Awarding Organization: Federal
    Investigators:Ogle, R.; Botchway,
    Vascularized Bone Grafts for Tissue Engineering
    Sponsoring Organization: NIH
    Date: 2008 - 2013
    Awarding Organization: Federal
    Investigators:Ogle, R.; Botchwey,
    Systems for Peripheral Nerve Repair
    Sponsoring Organization: NSF EFRI ( U. Conn, and UVA)
    Date: 2008 - 2011
    Awarding Organization: Federal
    Investigators:Ogle, R.; Laurencin, C.
    Production of EHS Tumor, Laminin and Reconstituted Basement Membrane
    Sponsoring Organization: Stemgent
    Date: 2008 - 2009
    Awarding Organization: Other
    Investigators:Ogle, R.
    The Adaptosome, a Nanoscale Delivery System for Specific Cell Targeting
    Sponsoring Organization: UVA NanoStar Seed Grant
    Date: 2008 - 2009
    Awarding Organization: Federal
    Investigators:Ogle, R.
    Cranial Bone Repair with Adipose-Derived Stem Cells
    Sponsoring Organization: NIH R21 DE15023-02
    Date: September 15, 2002 - October 15, 2005
    Investigators:Ogle, R.
    Regulation of Cranial Suture Morphogenesis
    Sponsoring Organization: NIH, 1 RO1 DE 10369-09
    Date: February 1, 1994 - July 31, 2005
    Investigators:Ogle, R.
    Regeneration of Calvarial Defects with Adipose-Derived Stem Cells
    Sponsoring Organization: Plastic Surgery Educational Foundation
    Date: July 1, 2002 - June 30, 2003
    Awarding Organization: Federal
    Investigators:Ogle, R.
    A Rat Model of the Developing Sagittal Suture
    Sponsoring Organization: Plastic Surgery Education Foundation
    Date: July 1, 2001 - June 30, 2002
    Awarding Organization: Federal
    Investigators:Ogle, R.
    Human Adipocytes in Fat Grafting Techniques
    Sponsoring Organization: Aesthetic Surgery Education and Research Foundation
    Date: July 1, 2001 - June 30, 2002
    Awarding Organization: Other
    Investigators:Ogle, R.; MacCrae, J.
    Quantification of Force Induces Cranial Suture Fusion in a Rat Model
    Sponsoring Organization: Maxillofacial Surgeons Foundation
    Date: January 1, 2001 - March 31, 2002
    Awarding Organization: Federal
    Investigators:Ogle, R.; Tholpady, S.; Lin, K.
    Growth Factor Regulation of Cranial Suture Morphogenesis
    Sponsoring Organization: NIH
    Date: July 1, 1996 - June 30, 2001
    Investigators:Ogle, R.; Opperman, L.
    Tissue Engineering of Auricular Cartilage, Research and Development Grant
    Sponsoring Organization: University of Virginia Medical Center
    Date: 1998 - 2000
    Awarding Organization: State
    Investigators:Ogle, R.; Lindsey, W.
    Tissue Engineering of Auricular Cartilage, Young Investator Grant
    Sponsoring Organization: American Academy of Facial Plastic and Reconstructive Surgery
    Date: 1998 - 2000
    Awarding Organization: Federal
    Investigators:Ogle, R.; Lindsey, W.
    Fibroblast Growth Factor Signaling in Cracial Suture Cells
    Sponsoring Organization: Plastic Surgery Education Foundation
    Date: July 1, 1997 - June 30, 1998
    Awarding Organization: Federal
    Investigators:Ogle, R.; Lin, K.
    Coronal Suture Transplant in Rabbits with Congenital Craniosynostosis
    Sponsoring Organization: March of Dimes
    Date: April 1, 1995 - March 31, 1997
    Awarding Organization: Federal
    Investigators:Ogle, R.; Mooney, M.; Pittsburgh, U.
    Repair of Bone with Extracellular Matrix
    Sponsoring Organization: NIH
    Date: April 1, 1994 - March 31, 1997
    Awarding Organization: Federal
    Investigators:Ogle, R.
    Skull Development in vitro
    Sponsoring Organization: Maxillofacial Surgeons Foundation
    Date: January 1, 1994 - December 31, 1995
    Awarding Organization: Other
    Investigators:Ogle, R.; Lin, K.
    Metastasis-Associate Integrins
    Sponsoring Organization: American Cancer Society CB-37A
    Date: July 1, 1992 - December 31, 1995
    Awarding Organization: Federal
    Investigators:Ogle, R.
    Growth Factors in Human Hemangiomas
    Sponsoring Organization: Plastic Surgery Education Foundation
    Date: July 1, 1994 - June 30, 1995
    Awarding Organization: Federal
    Investigators:Ogle, R.; Gampper, T.
    Molecular Analysis of Abnormalities Associated with Craniosynostosis
    Sponsoring Organization: Plastic Surgery Education Foundation, Faculty Sponsor for T. Gampper
    Date: July 1, 1993 - June 30, 1995
    Awarding Organization: Federal
    Investigators:Ogle, R.
    In Vitro Definition of Cellular Abnormalities Associated with Craniosynostosis
    Sponsoring Organization: Maxillofacial Surgeons Foundation
    Date: July 1, 1993 - December 31, 1994
    Awarding Organization: Other
    Investigators:Ogle, R.; Persing, J.
    Repair of Bone with Collagen Gels and Osteoblasts, Faculty Sponsor for T. M. Sweeney
    Sponsoring Organization: Orthopedic Research and Education Foundation
    Date: July, 1993 - June, 1994
    Awarding Organization: Federal
    Investigators:Ogle, R.
    The Role of Basement Membranes in Osteogenesis
    Sponsoring Organization: Jeffress Memorial Trust
    Date: 1991 - 1993
    Awarding Organization: Federal
    Investigators:Ogle, R.
    An In Vitro model of Metastasis for Squamous Cell Carcinoma
    Sponsoring Organization: Plastic Surgery Education Foundation, Faculty Sponsor for Edward Ricciardelli
    Date: July 1, 1992 - June 30, 1993
    Awarding Organization: Federal
    Investigators:Ogle, R.
    Repair of Bone Defects with Extracellular Matrix Gels
    Sponsoring Organization: Plastic Surgery Education Foundation, Faculty Sponsor for T.M. Sweeney
    Date: July 1, 1992 - June 30, 1993
    Awarding Organization: Federal
    Investigators:Ogle, R.
    Basement Membranes of Hemangioma Endothelial Cells
    Sponsoring Organization: Plastic Surgery Education Foundation, Faculty Sponsor to D. Wang
    Date: July, 1991 - June, 1992
    Awarding Organization: Federal
    Investigators:Ogle, R.
    Cellular biology of Craniofacial Intramembranous Ossification
    Sponsoring Organization: Plastic Surgery Educatin Foundation
    Date: July 1, 1991 - June, 1992
    Awarding Organization: Other
    Investigators:Ogle, R.; Persing, J.
    The Sutural/Dural Interrelationship in Maintaining Sutural Patency During Development of the Skull
    Sponsoring Organization: Maxillofacial Surgeons Foundations
    Date: July 1, 1991 - June 30, 1992
    Awarding Organization: Other
    Investigators:Ogle, R.; Persing, J.
    Metastasis-Associated Integrins
    Sponsoring Organization: American Cancer Society Institutional, UVa
    Date: January 1, 1991 - December 31, 1991
    Awarding Organization: Federal
    Investigators:Ogle, R.
    Struture, Function, and Expression of Basement Membrane Receptors in the Embryo
    Sponsoring Organization: March of Dimes Basil O'Connor Award
    Date: September 1, 1988 - August 31, 1991
    Awarding Organization: Federal
    Investigators:Ogle, R.
    Cellular and Molecular Biology of Cardiac Morphogenesis
    Sponsoring Organization: NIH
    Date: September 1, 1986 - August 31, 1991
    Awarding Organization: Federal
    Investigators:Ogle, R.; Little, C.
    The Role of Laminin and its Receptor in Cardiac Endothelial Cell Differentiation
    Sponsoring Organization: American Heart Association
    Date: July 1, 1988 - June 30, 1990
    Awarding Organization: Federal
    Investigators:Ogle, R.
    Adhesion of Metastatic Melanoma Cells to Collagen IV
    Sponsoring Organization: American Cancer Society Institutional Award, MUSC
    Date: February 1, 1988 - January 31, 1989
    Awarding Organization: Federal
    Investigators:Ogle, R.
    Characterization of Collagen and Laminin Receptors
    Sponsoring Organization: Upjohn
    Date: 1986
    Awarding Organization: Federal
    Investigators:Ogle, R.
    National Research Service Award (Predoctoral)
    Sponsoring Organization: NIH
    Date: 1984 - 1985
    Awarding Organization: Federal
    Investigators:Ogle, R.
  • Intellectual Property

    "Basement membrane Compositions and applications thereof:
    Patent/Copyright: Patent
    Type: Regular
    Patent Nationality: United States
    Inventors:
    Ogle, R.
    "Compositions and Methods for Making and Using Laminin Nanofiber"
    Patent/Copyright: Patent
    Inventors:
    Ogle, R.
    Botchwey and Neal, UVa,
    "Compositions and Methods for Making and Using Laminin Nanofiber"
    Patent/Copyright: Patent
    Inventors:
    Ogle, R.
    Botchwey and Neal, UVa,
    "Compositions and methods for use of hybrid biomaterials comprised of laminin or laminin containing extracts blended with biodegradable polymers"
    Patent/Copyright: Patent
    Inventors:
    Ogle, R.
    Botchwey,
    "Isolation of basement memberane components from tissues and applications thereof"
    Patent/Copyright: Patent
    Inventors:
    Ogle, R.
    , L.
    "Meningeal-derived stem cells applications"
    Patent/Copyright: Patent
    Inventors:
    Ogle, R.
    Tholpady,
    "Parallel Rod Electrical Point Charge Aligned Nanofibers"
    Patent/Copyright: Patent
    Inventors:
    Ogle, R.
    Francis,
    LifeNet Health,
    "Liquefaction of Bone Matrix"
    Patent/Copyright: Patent
    Type: Regular
    Inventors:
    Ogle, R.
    "Liquefaction of Bone Matrix"
    Patent/Copyright: Patent
    Inventors:
    Ogle, R.
    Francis,
    LifeNet Health,
    "Compositions and Methods for Making and Using Laminin Nanofiber"
    Patent/Copyright: Patent
    Type: Regular
    Patent Nationality: United States
    Inventors:
    Ogle, R.
    "Compositions and methods for making and using laminin nanofibers
    Patent/Copyright: Patent
    Type: Regular
    Patent Nationality: United States
    Inventors:
    Ogle, R.
    ,
    "Compositions and Methods for Making and Using Laminin Nanofibers"
    Patent/Copyright: Patent
    Patent Nationality: United States
    Inventors:
    Ogle, R.
    "Compositions and Methods for Making and Using Laminin Nanofibers"
    Patent/Copyright: Patent
    Cooperation Treaty: licensed by Stemgent, Cambridge, MA
    Inventors:
    Ogle, R.
    Meningeal Derived Stem Cells
    Patent/Copyright: Patent
    Type: Regular
    Patent Nationality: United States
    Inventors:
    Ogle, R.
    Tholpady,