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Bioelectrics Calendar

CBE Seminar - Aude Silve, PhD, Karlsruhe Inst. Technology, Karlsruhe, Germany

R
 - time/details may vary.
 
Date/time
02/11/2014 9:00 AM - 02/11/2014 10:00 AM
Location
IRP2 1st Floor Conference Room
Description
"Electropermeabilisation with micropulses and nanopulses: any difference at all?"

"Electropermeabilisation with micropulses and nanopulses: any difference at all?"

Aude Silve, Ph.D.

Postdoctoral Fellow

Wolfgang Frey's group

Karlsruhe Institute of Technology (KIT)

Karlsruhe, Germany

http://www.ihm.kit.edu/english/311_496.php

Tuesday, February 11, 2014, 9-10AM

IRP2 First Floor Conference Room

4211 Monarch Way

Anyone who has been dealing with both the classical 'long' pulses (microsecond or millisecond range) and the much more fashionable 'short' ones (in the nanosecond range) will agree that moving from micro to nano made everything more expensive (generators, oscilloscopes, probes) and more complicated from the metrology point of view. However, most electropermeabilisation results are strikingly similar whatever the pulse duration. Is it therefore worth the effort?

With this in mind, this talk will focus on the parallel between the long and the short pulses. Several aspects of electropermeabilisation will be addressed: electromagnetic modeling, efficiency of electropermeabilisation in vitro, resealing time, effect of repetition rate and electrical properties of a permeabilized membrane. Hoping to point out all the similarities to better understand the real differences.