CBE Seminar - Aude Silve, PhD, Karlsruhe Inst. Technology, Karlsruhe, Germany
- 02/11/2014 9:00 AM - 02/11/2014 10:00 AM
- IRP2 1st Floor Conference Room
- "Electropermeabilisation with micropulses and nanopulses: any difference at all?"
"Electropermeabilisation with micropulses and nanopulses: any difference at all?"
Aude Silve, Ph.D.
Wolfgang Frey's group
Karlsruhe Institute of Technology (KIT)
Tuesday, February 11, 2014, 9-10AM
IRP2 First Floor Conference Room
4211 Monarch Way
Anyone who has been dealing with both the classical 'long' pulses (microsecond or millisecond range) and the much more fashionable 'short' ones (in the nanosecond range) will agree that moving from micro to nano made everything more expensive (generators, oscilloscopes, probes) and more complicated from the metrology point of view. However, most electropermeabilisation results are strikingly similar whatever the pulse duration. Is it therefore worth the effort?
With this in mind, this talk will focus on the parallel between the long and the short pulses. Several aspects of electropermeabilisation will be addressed: electromagnetic modeling, efficiency of electropermeabilisation in vitro, resealing time, effect of repetition rate and electrical properties of a permeabilized membrane. Hoping to point out all the similarities to better understand the real differences.