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Bioelectrics Calendar

CBE Seminar - David Mu, PhD, Eastern Virginia Medical School

R
 - time/details may vary.
 
Date/time
10/08/2013 9:00 AM - 10/08/2013 10:00 AM
Location
IRP2 1st Floor Conference Room
Description
"Discovery of an amplified lung cancer gene and its connections to microRNAs"

"Discovery of an amplified lung cancer gene and its connections to microRNAs"

Seminar: Tuesday, October 8, 2013, 9-10AM

David Mu, PhD

Associate Professor

Department of Microbiology and Molecular Cell Biology

Leroy T. Canoles Jr. Cancer Research Center

Eastern Virginia Medical School

http://www.evms.edu/research/centers_institutes_departments/microbiology_molecular_cell_biology/labs/david_mu_phd/

We and others discovered that NKX2-1 is recurrently amplified in human lung cancer, implicating that NKX2-1 is an oncogene. Later studies suggest that NKX2-1 exhibits anti-oncogenic activities. By connecting NKX2-1 to the microRNA signaling network, we afford new insight on the dual functionalities of this critical lung cancer gene.