CBE Seminar - Julie Gehl, MD PhD, Copenhagen University Hospital Herlev, Herlev, Denmark
- 10/21/2011 10:00 AM - 10/21/2011 11:00 AM
- IRP2 1st Floor Conference Room
- "Drug and gene delivery by electroporation: What we've learnt, where the technology could go and how it would get there"
"Drug and gene delivery by electroporation: What we've learnt, where the technology could go and how it would get there"
Julie Gehl, MD PhD
Center for Experimental Drug and Gene Electrotransfer
Copenhagen University Hospital Herlev
Friday, October 21, 2011, 10-11 AM
IRP2 First Floor Conference Room
4211 Monarch Way (near Ted Constant Center)
Dr. Gehl's Research:
Electroporation based drug and gene delivery offers new perspectives in the treatment of cancer, chronic diseases, and in the case of DNA vaccination actually for everyone. It's been convincingly shown how drug delivery by electroporation may efficiently eliminate tumors, and currently electrode systems are being developed also for treatment of internal tumors, e.g. in the brain. One focus of the talk will be how an oncologists perspective on the future use of electrochemotherapy could be. Another major focus of electroporation is its use in gene therapy. We've only scratched the surface of the possibilities of gene therapy in the treatment of cancer, in a number of chronic diseases as well as widespread use for DNA vaccination.
Elements particular for gene transfer by electroporation will be discussed, i.e. how expression duration and levels may be controlled. Dr. Gehl is an oncologist, and has also worked with basic and clinical research on drug and gene electrotransfer for over 15 years. She heads the Center for Experimental Drug and Gene Electrotransfer at Copenhagen University Hospital Herlev and is an Oncology Research Fellow of the Royal Swedish Academy of Sciences.